CAS 7093-67-6

pentaglycine

Description:

Pentaglycine is a peptide composed of five glycine amino acid residues linked together by peptide bonds. Its chemical formula is C10H17N5O5, and it is characterized by its relatively simple structure, which consists solely of the amino acid glycine, the simplest amino acid with a single hydrogen atom as its side chain. Pentaglycine is known for its role in the structure of certain proteins and peptides, particularly in bacterial cell walls, where it contributes to the stability and integrity of the peptidoglycan layer. The substance is typically a white crystalline solid and is soluble in water, reflecting the hydrophilic nature of glycine. Pentaglycine can be synthesized through various methods, including solid-phase peptide synthesis. Its properties, such as melting point and solubility, can vary depending on the conditions of synthesis and purification. Due to its structural simplicity, pentaglycine serves as a model compound for studying peptide interactions and folding, as well as for applications in biochemistry and molecular biology.

Formula: C₁₀H₁₇N₅O₆

InChI: InChI=1/C10H17N5O6/c11-1-6(16)12-2-7(17)13-3-8(18)14-4-9(19)15-5-10(20)21/h1-5,11H2,(H,12,16)(H,13,17)(H,14,18)(H,15,19)(H,20,21)

SMILES: C(C(=NCC(=NCC(=NCC(=NCC(=O)O)O)O)O)O)N

Synonyms:

• Gly-Gly-Gly-Gly-Gly
• Glycylglycylglycylglycylglycine
• H-GLY-GLY-GLY-GLY-GLY-OH
• Glycine, N-[N-[N-(N-glycylglycyl)glycyl]glycyl]-
• N-[N-[N-(N-glycylglycyl)glycyl]glycyl]glycine
• 2-[[2-[[2-[[2-(glycylamino)acetyl]amino]acetyl]amino]acetyl]amino]acetic acid

H-Gly-Gly-Gly-Gly-Gly-OH

CAS: 7093-67-6

Pentaglycine forms stable 4N-coordinated Cu(II) complexes.

Formula: C₁₀H₁₇N₅O₆

Purity: 95.28%

Color and Shape: White Powder

Molecular weight: 303.28

Ref: 01-4006911

2-[[2-[[2-[[2-[(2-aminoacetyl)amino]acetyl]amino]acetyl]amino]acetyl]amino]acetic acid

CAS: 7093-67-6

Formula: C₁₀H₁₇N₅O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 303.2719

Ref: IN-DA005FKX

Pentaglycine

CAS: 7093-67-6

Pentaglycine

Purity: ≥95%

Molecular weight: 303.27g/mol

Ref: 54-OR1032259

Gly-Gly-Gly-Gly-Gly-OH

CAS: 7093-67-6

Gly-Gly-Gly-Gly-Gly-OH is a pentaglycine that inhibits bacterial growth by binding to the penicillin-binding proteins (PBPs) in the bacterial cell wall. Gly-Gly-Gly-Gly-OH binds to the PBPs, preventing the formation of an antibiotic inhibitor complex with the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis. The kinetic energy of Gly-Gly-Gylo-OH is measured using titration calorimetry. The reaction mechanism is shown below:

Formula: C₁₀H₁₇N₅O₆

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 303.27 g/mol

Ref: 3D-FG49307

Pentaglycine

CAS: 7093-67-6

Formula: C₁₀H₁₇N₅O₆

Purity: 98%

Color and Shape: Solid, White powder

Molecular weight: 303.275

Ref: 10-F300021

Pentaglycine

Controlled Product

CAS: 7093-67-6

Applications PENTAGLYCINE (cas# 7093-67-6) is a useful research chemical.

Formula: C₁₀H₁₇N₅O₆

Color and Shape: Neat

Molecular weight: 303.27

Ref: TR-P227643