CAS 70989-04-7

(+)-Mephenytoin

Description:

(+)-Mephenytoin, with the CAS number 70989-04-7, is a pharmaceutical compound primarily used as an anticonvulsant. It is a member of the hydantoin class of drugs and is characterized by its chiral nature, existing as a single enantiomer, which is the (+) form. This compound is typically administered in its racemic form, but the (+) enantiomer is noted for its specific pharmacological activity. (+)-Mephenytoin exhibits a mechanism of action that involves the stabilization of neuronal membranes and the inhibition of repetitive neuronal firing, making it effective in the management of epilepsy. The substance is generally soluble in organic solvents and has a relatively low solubility in water. Its chemical structure includes a phenyl group, which contributes to its lipophilicity, influencing its absorption and distribution in the body. As with many anticonvulsants, monitoring for side effects and interactions with other medications is essential during treatment. Overall, (+)-Mephenytoin plays a significant role in the therapeutic landscape for seizure disorders.

Formula: C₁₂H₁₄N₂O₂

InChI: InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m0/s1

InChI key: InChIKey=GMHKMTDVRCWUDX-LBPRGKRZSA-N

SMILES: C(C)[C@@]1(C(=O)N(C)C(=O)N1)C2=CC=CC=C2

Synonyms:

• (+)-5-Ethyl-3-methyl-5-phenylhydantoin
• (+)-Mephenytoin
• (+)-Mesantoin
• (5S)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
• (5S)-5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
• (S)-5-Ethyl-3-methyl-5-phenylhydantoin=(S)-Mephenytoin
• (S)-5-Ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
• 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (5S)-
• 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (S)-
• d-Mephenytoin
• (S)-Mephenytoin

(S)-Mephenytoin

CAS: 70989-04-7

Formula: C₁₂H₁₄N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 218.2518

Ref: IN-DA0061JQ

(S)-Mephenytoin

CAS: 70989-04-7

Formula: C₁₂H₁₄N₂O₂

Color and Shape: White To Off-White Solid

Molecular weight: 218.26

Ref: 4Z-M-045

(S)-(+)-Mephenytoin

CAS: 70989-04-7

Formula: C₁₂H₁₄N₂O₂

Purity: ≥ 98.0%

Color and Shape: White to off-white solid

Molecular weight: 218.25

Ref: 7W-GL8711

(S)-5-Ethyl-3-Methyl-5-Phenylimidazolidine-2,4-Dione

CAS: 70989-04-7

(S)-5-Ethyl-3-Methyl-5-Phenylimidazolidine-2,4-Dione

Purity: 99%

Molecular weight: 218.25g/mol

Ref: 54-OR1024086

(S)-Mephenytoin

CAS: 70989-04-7

(S)-Mephenytoin

Purity: ≥98%

Molecular weight: 218.25g/mol

Ref: 54-BUP07237

(S)-Mephenytoin

CAS: 70989-04-7

(S)-Mephenytoin: (+)-enantiomer, anticonvulsant, CYP2C19 substrate for analyzing CYP450 metabolism.

Formula: C₁₂H₁₄N₂O₂

Purity: 98.73% - 99.82%

Color and Shape: Solid

Molecular weight: 218.25

Ref: TM-T21529

(S)-Mephenytoin

CAS: 70989-04-7

Applications An anticonvulsant agent.
References Shimada, et al.: Anal. Biochem., 147, 174 (1975), Dzhagatspanyan. IA., et al.: Pharm. Chem. J., 25, 181 (1991),

Formula: C₁₂H₁₄N₂O₂

Color and Shape: Off-White

Molecular weight: 218.25

Ref: TR-M225000

(S)-Mephenytoin - Bio-X ™

CAS: 70989-04-7

(S)-Mephenytoin is a substrate of cytochrome P450 enzyme CYP2C19 (a hydroxylase). It is an effective anticonvulsant that improves control of seizures in patients. According to studies, the drug exhibits a genetic polymorphism in CYP2C19 that results in reduced metabolism in some individuals.

Formula: C₁₂H₁₄N₂O₂

Purity: Min. 97 Area-%

Color and Shape: White Powder

Molecular weight: 218.25 g/mol

Ref: 3D-FM25065

(S)-Mephenytoin

CAS: 70989-04-7

Formula: C₁₂H₁₄N₂O₂

Molecular weight: 218.26

Ref: ST-EA-CP-M129001