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CAS 70989-04-7

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(+)-Mephenytoin

Description:
(+)-Mephenytoin, with the CAS number 70989-04-7, is a pharmaceutical compound primarily used as an anticonvulsant. It is a member of the hydantoin class of drugs and is characterized by its chiral nature, existing as a single enantiomer, which is the (+) form. This compound is typically administered in its racemic form, but the (+) enantiomer is noted for its specific pharmacological activity. (+)-Mephenytoin exhibits a mechanism of action that involves the stabilization of neuronal membranes and the inhibition of repetitive neuronal firing, making it effective in the management of epilepsy. The substance is generally soluble in organic solvents and has a relatively low solubility in water. Its chemical structure includes a phenyl group, which contributes to its lipophilicity, influencing its absorption and distribution in the body. As with many anticonvulsants, monitoring for side effects and interactions with other medications is essential during treatment. Overall, (+)-Mephenytoin plays a significant role in the therapeutic landscape for seizure disorders.
Formula:C12H14N2O2
InChI:InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m0/s1
InChI key:InChIKey=GMHKMTDVRCWUDX-LBPRGKRZSA-N
SMILES:C(C)[C@@]1(C(=O)N(C)C(=O)N1)C2=CC=CC=C2
Synonyms:
  • (+)-5-Ethyl-3-methyl-5-phenylhydantoin
  • (+)-Mephenytoin
  • (+)-Mesantoin
  • (5S)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
  • (5S)-5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
  • (S)-5-Ethyl-3-methyl-5-phenylhydantoin=(S)-Mephenytoin
  • (S)-5-Ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
  • 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (5S)-
  • 2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (S)-
  • d-Mephenytoin
  • (S)-Mephenytoin
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