CAS 71-00-1

L-Histidine

Description:

L-Histidine is an essential amino acid that plays a crucial role in various biological processes. It is classified as a polar, positively charged amino acid due to the presence of an imidazole side chain, which can participate in hydrogen bonding and metal ion coordination. L-Histidine is involved in the synthesis of proteins and is a precursor for histamine, a vital neurotransmitter. It has a pKa value around 6.0, indicating that it can act as both an acid and a base, making it important in buffering systems within biological fluids. This amino acid is also known for its role in enzyme catalysis and is found in hemoglobin, contributing to oxygen transport in the blood. L-Histidine is soluble in water and has a relatively high melting point. It is commonly found in dietary sources such as meat, fish, dairy products, and certain grains, making it essential for human health, particularly in growth and tissue repair.

Formula: C₆H₉N₃O₂

InChI: InChI=1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1

InChI key: InChIKey=HNDVDQJCIGZPNO-YFKPBYRVSA-N

SMILES: C([C@@H](C(O)=O)N)C1=CN=CN1

Synonyms:

• (2S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid
• (2S)-2-Azaniumyl-3-(1H-imidazol-5-yl)propanoate
• (S)-2-Amino-3-(1H-imidazol-4-yl)propanoic acid
• (S)-4-(2-Amino-2-carboxyethyl)imidazole
• (S)-Histidine
• (S)-α-Amino-1H-imidazole-4-propanoic acid
• 103: PN: WO2021061872 SEQID: 103 claimed protein
• 124: PN: WO2020191245 SEQID: 252 claimed protein
• 1H-Imidazole-4-alanine, (S)-
• 1H-Imidazole-4-propanoic acid, α-amino-, (S)-
• <span class="text-smallcaps">L</span>-(-)-Histidine
• <span class="text-smallcaps">L</span>-Alanine, 3-(1H-imidazol-4-yl)-
• Glyoxaline-5-alanine
• Histidin
• Histidina
• Histidine
• Histidine, <span class="text-smallcaps">L</span>-
• Histidine, L-
• L-Alanine, 3-(1H-imidazol-4-yl)-
• L-Hystidine
• Nsc 137773
• (S)-2-Amino-3-(4-imidazolyl)propionic acid~H-His-OH
• L-Histidine Base
• L-HIS = H-His-OH
• L-Histidine
• H-His-OH
• L-Histidine,free base
• His

L-Histidine (base) extrapure CHR, 99%

CAS: 71-00-1

Formula: C₆H₉N₃O₂

Purity: min. 99 %

Color and Shape: White, Crystalline powder, Clear, Colourless

Molecular weight: 155.16

Ref: SR-94495

L-Histidine

CAS: 71-00-1

L-histidine is a molecule that chelates metal ions and inhibits their function. L-Histidine is used as an analytical reagent for the determination of metal ions in water, a polymerase chain reaction (PCR) inhibitor, and an immunosuppressant. L-histidine is also used to treat bowel disease and cancer by inhibiting the production of certain molecules. L-histidine has been shown to bind to toll-like receptor 4 (TLR4) in intestinal cells, which activates the immune system to produce cytokines such as IL-8. In addition, L-histidine can act as a cofactor for enzymes involved in protein synthesis by protecting them from oxidation. L histidine can also be found in the protein that binds with gold particles, forming colloidal gold

Formula: C₆H₉N₃O₂

Color and Shape: White Powder

Molecular weight: 155.15 g/mol

Ref: 3D-FH15651