CAS 71-27-2

Succinylcholine chloride

Description:

Succinylcholine chloride is a synthetic, depolarizing neuromuscular blocker commonly used in medical settings, particularly for facilitating intubation and providing muscle relaxation during surgical procedures. It is a quaternary ammonium compound derived from the combination of two acetylcholine molecules, which leads to its action on the neuromuscular junction. The substance is characterized by its rapid onset and short duration of action, typically lasting only a few minutes, making it ideal for short surgical interventions. Succinylcholine acts by binding to nicotinic acetylcholine receptors at the motor end plate, causing an initial muscle contraction followed by paralysis due to sustained depolarization. It is important to note that its use can be associated with side effects, including hyperkalemia, malignant hyperthermia, and bradycardia. Due to its pharmacological properties, succinylcholine is classified as a Schedule IV controlled substance in some jurisdictions, and its administration should be carefully monitored by healthcare professionals.

Formula: C₁₄H₃₀N₂O₄·2Cl

InChI: InChI=1S/C14H30N2O4.2ClH/c1-15(2,3)9-11-19-13(17)7-8-14(18)20-12-10-16(4,5)6;;/h7-12H2,1-6H3;2*1H/q+2;;/p-2

InChI key: InChIKey=YOEWQQVKRJEPAE-UHFFFAOYSA-L

SMILES: C([N+](C)(C)C)COC(CCC(OCC[N+](C)(C)C)=O)=O.[Cl-]

Synonyms:

• (2-Hydroxyethyl)trimethylammonium chloride succinate
• 2,2-Succinyldioxybis(Ethyltrimethylammonium) Dichloride
• 2-Dimethylaminoethyl succinate dimethochloride
• Anectine
• Anectine chloride
• Bis(2-dimethylaminoethyl) succinate bis(methochloride)
• Choline succinate dichloride
• Choline, chloride, succinate (2:1)
• Choline,chloride succinate
• Diacetylcholine dichloride
• Ethanaminium, 2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, chloride (1:2)
• Ethanaminium, 2,2′-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-, dichloride
• Lysthenon
• Lysthenone
• Midarine
• Myoplegine
• Pantolax
• Quelicin
• Quelicin chloride
• Querlicin
• Scoline
• Scoline chloride
• Skolin
• Succicuran
• Succin
• Succinic acid bis[β-dimethylaminoethyl] ester dimethochloride
• Succinic acid, diester with choline chloride
• Succinolin
• Succinoylcholine chloride
• Succinyl bischoline chloride
• Succinyl-asta
• Succinylbischoline dichloride
• Succinylcholine chloride
• Succinylcholine dichloride
• Succinyldicholine chloride
• Succinylforte
• Sucostrin
• Sucostrin chloride
• Sukolin

Succinylcholine Chloride Dihydrate

CAS: 6101-15-1, 71-27-2

Formula: C₁₄H₃₀Cl₂N₂O₄·2H₂O

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 397.33

Ref: 3B-S0149

Succinylcholine Chloride

CAS: 71-27-2

Formula: C₁₄H₃₀N₂O₄·2Cl

Molecular weight: 290.40 2 35.45

Ref: 4Z-C-5916

Succinylcholine Chloride

Controlled Product

CAS: 71-27-2

Stability Hygroscopic
Applications A neuromuscular blocking agent. Muscle relaxant (skeletal).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jensen, B., et al.: Acta Chem. Scand., 30, 1002 (1976), Anttila, P., et al.: Med. Biol., 56, 152 (1978), Foss, P.R.B., et al.: Anal. Profiles Drug Subs., 10, 691 (1981),

Formula: C₁₄H₃₀N₂O₄·2Cl

Color and Shape: Neat

Molecular weight: 361.30

Ref: TR-S692100

Succinylcholine Chloride-13C6

Controlled Product

CAS: 71-27-2

Applications A neuromuscular blocking agent. Muscle relaxant (skeletal).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Jensen, B., et al.: Acta Chem. Scand., 30, 1002 (1976), Anttila, P., et al.: Med. Biol., 56, 152 (1978), Foss, P.R.B., et al.: Anal. Profiles Drug Subs., 10, 691 (1981),

Formula: C₆C₈H₃₀N₂O₄·2Cl

Color and Shape: Neat

Molecular weight: 367.261

Ref: TR-S692102

Succinylcholine chloride

CAS: 71-27-2

Succinylcholine chloride is a muscle relaxant that has been used to treat herpes simplex virus, congenital heart disease, and other conditions. Succinylcholine chloride is an ester of succinic acid and choline. It binds to the acetylcholine receptor on the postsynaptic membrane of skeletal muscles, which leads to depolarization and contraction. The binding of succinylcholine to its receptor triggers an influx of sodium ions into the cell, which causes membrane depolarization and muscle relaxation. Succinylcholine chloride has been shown to have neurotrophic effects in a study where it was administered to mice with experimental myocardial infarction. This drug also has been shown to increase microvessel density in pigs with intubation.

Formula: C₁₄H₃₀Cl₂N₂O₄

Purity: (Hplc) Min. 96%

Color and Shape: Powder

Molecular weight: 361.3 g/mol

Ref: 3D-FS27921