CAS 71012-19-6

Asialoganglioside GM1

Description:

Asialoganglioside GM1 is a glycosphingolipid that is a derivative of ganglioside GM1, characterized by the absence of sialic acid residues. This modification alters its biological properties and interactions. Asialoganglioside GM1 is primarily found in the membranes of certain cells and plays a significant role in cell recognition, signaling, and adhesion processes. It is particularly important in the context of neuronal function and development. The structure of asialoganglioside GM1 consists of a ceramide backbone linked to a carbohydrate moiety, which includes glucose and galactose units. This compound is often studied for its potential applications in drug delivery systems and as a target for specific cellular interactions, particularly in the context of cancer research and immunology. Its unique properties make it a valuable subject of investigation in both basic and applied sciences, particularly in understanding cell surface interactions and the role of glycosphingolipids in health and disease.

Formula: C₆₂H₁₁₄N₂O₂₃

InChI: InChI=1/C62H114N2O23/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-46(71)64-40(41(70)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2)38-80-60-54(78)51(75)57(44(36-67)83-60)86-62-55(79)52(76)56(45(37-68)84-62)85-59-47(63-39(3)69)58(49(73)43(35-66)81-59)87-61-53(77)50(74)48(72)42(34-65)82-61/h30,32,40-45,47-62,65-68,70,72-79H,4-29,31,33-38H2,1-3H3,(H,63,69)(H,64,71)/b32-30+/t40?,41?,42-,43-,44-,45-,47-,48+,49+,50+,51-,52-,53-,54-,55-,56+,57-,58-,59+,60?,61+,62+/m1/s1

Synonyms:

• Asialo GM1 ganglioside
• Asialo GM1
• Asialo GM1 glycolipid
• Ganglio-N-tetraosylceramide
• Ganglioside, asialo GM1
• Ganglioside GA1, de(N-acetyl-alpha-neuraminosyl)-(2-3B)
• Ceramide tetrahexoside
• Ganglioside GM1
• Asialo
• Gangliotetraosyl ceramide
• GM1
• Monosialotetrahexosylganglioside
• Chromium
• N-{(1S,2R,3E)-1-[(beta-D-glucopyranosyloxy)methyl]-2-hydroxyheptadec-3-en-1-yl}tetracosanamide
• N-{(1S,2R,3E)-1-[(beta-D-glucopyranosyloxy)methyl]-2-hydroxyheptadec-3-en-1-yl}docosanamide
• N-[(2S,3R,4E)-1-(beta-D-glucopyranosyloxy)-3-hydroxyoctadec-4-en-2-yl]octadecanamide
• (2S,4R,5S,6S)-2-[(2S,3R,4R,5S,6R)-5-[(2S,3R,4R,5R,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-2-[(2R,3S,4R,5R,6R)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(E)-3-hydroxy-2-(octadecanoylamino)octadec-4-enoxy]tetrahydropyran-3-yl]oxy-3-hydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxy-5-amino-6-[3-[(2R,4R,5S,6S)-5-amino-2-carboxy-4-hydroxy-6-(1,2,3-trihydroxypropyl)tetrahydropyran-2-yl]oxy-1,2-dihydroxy-propyl]-4-hydroxy-tetrahydropyran-2-carboxylic acid

Ganglioside GM1 Asialo Mixture

CAS: 71012-19-6

GM1 asialo, a cleaved GM1 ganglioside, boosts host defense against P. aeruginosa and RSV, affecting NK and T cells and IFN-γ levels.

Formula: C₆₂H₁₁₄N₂O₂₃

Color and Shape: Solid

Molecular weight: 1255.585

Ref: TM-T37295

Gangliotetraosyl Ceramide Gg4

CAS: 71012-19-6

Formula: Unspecified

Purity: >98%

Color and Shape: Solid

Ref: 48-56-1102

GA1-Ganglioside

CAS: 71012-19-6

Formula: C₆₂H₁₁₄N₂O₂₃

Purity: ≥ 98%

Color and Shape: White to light-yellow solid or powder

Molecular weight: 1255.6

Ref: 7W-GC0885

GA1-Ganglioside

CAS: 71012-19-6

GA1-ganglioside is also known as asialo-GM1 ganglioside. Autoimmune responses to GA1 ganglioside and high titers of anti-GA1 antibodies have been associated with neuromotor disorders, such as, motor neuron disease, multifocal motor neuropathy, and Guillain-Barré syndrome (Kolter, 2006). Anti-GA1 antibodies are also associated with Borrelia burgdorferi infection and Lyme disease (Djellaoui, 2016).

Formula: C₆₂H₁₁₄N₂O₂₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 1,255.57 g/mol

Ref: 3D-OG16191