CymitQuimica logo

CAS 71030-37-0

:

12-HETE

Description:
12-HETE, or 12-Hydroxyeicosatetraenoic acid, is a bioactive lipid and a member of the eicosanoid family, derived from arachidonic acid through the action of lipoxygenase enzymes. It is characterized by its hydroxyl group at the 12th carbon position of the eicosatetraenoic acid chain, which contributes to its biological activity. 12-HETE plays a significant role in various physiological processes, including inflammation, cell signaling, and the regulation of vascular tone. It is known to influence platelet aggregation and has been implicated in the pathophysiology of several diseases, including cardiovascular disorders and cancer. The compound is typically found in biological systems, particularly in platelets and other immune cells. Its synthesis and metabolism are tightly regulated, and it can act through specific receptors to exert its effects. Due to its involvement in critical biological pathways, 12-HETE is of interest in pharmacological research and therapeutic applications.
Formula:C20H32O3
InChI:InChI=1/C20H32O3/c1-2-3-4-5-10-13-16-19(21)17-14-11-8-6-7-9-12-15-18-20(22)23/h7-11,13-14,17,19,21H,2-6,12,15-16,18H2,1H3,(H,22,23)/b9-7-,11-8-,13-10-,17-14+
InChI key:InChIKey=ZNHVWPKMFKADKW-VXBMJZGYNA-N
SMILES:C(\C(C/C=C\CCCCC)O)=C/C=C\C/C=C\CCCC(O)=O
Synonyms:
  • 12-Hydroxy-5,8,10,14-eicosatetraenoic acid
  • (5Z,8Z,10E,14Z)-12-Hydroxy-5,8,10,14-eicosatetraenoic acid
  • 5,8,10,14-Eicosatetraenoic acid, 12-hydroxy-, (5Z,8Z,10E,14Z)-
  • 12-Hydroxyeicosatetraenoic acid
  • 5,8,10,14-Eicosatetraenoic acid, 12-hydroxy-, (E,Z,Z,Z)-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 3 products.