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CAS 71030-38-1

:

11-HETE

Description:
11-HETE, or 11-hydroxyeicosatetraenoic acid, is a bioactive lipid belonging to the eicosanoid family, specifically a type of hydroxyeicosanoid derived from arachidonic acid. It is characterized by its role as a signaling molecule in various physiological processes, including inflammation and vascular function. 11-HETE is produced through the action of lipoxygenase enzymes, which convert arachidonic acid into various hydroxylated derivatives. This compound is known to influence cell proliferation, migration, and differentiation, making it significant in both normal physiological and pathological conditions. Its presence has been implicated in various biological processes, including immune responses and the modulation of blood pressure. Additionally, 11-HETE can interact with specific receptors, contributing to its biological effects. The study of 11-HETE and its derivatives is important in understanding their potential therapeutic applications, particularly in the context of cardiovascular diseases and inflammatory disorders. As a chemical substance, it is typically analyzed using techniques such as chromatography and mass spectrometry for research and clinical purposes.
Formula:C20H32O3
InChI:InChI=1/C20H32O3/c1-2-3-4-5-7-10-13-16-19(21)17-14-11-8-6-9-12-15-18-20(22)23/h6-7,9-11,13-14,16,19,21H,2-5,8,12,15,17-18H2,1H3,(H,22,23)/b9-6-,10-7-,14-11-,16-13+
InChI key:InChIKey=GCZRCCHPLVMMJE-RLZWZWKONA-N
SMILES:C(C/C=C\C/C=C\CCCC(O)=O)(/C=C/C=C\CCCCC)O
Synonyms:
  • 11-HETE
  • 5,8,12,14-Eicosatetraenoic acid, 11-hydroxy-, (E,Z,Z,Z)-
  • (5Z,8Z,12E,14Z)-11-Hydroxy-5,8,12,14-eicosatetraenoic acid
  • 5,8,12,14-Eicosatetraenoic acid, 11-hydroxy-, (5Z,8Z,12E,14Z)-
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