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CAS 7104-38-3

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Methotrimeprazine maleate

Description:
Methotrimeprazine maleate is an antipsychotic medication primarily used for its sedative and antiemetic properties. It belongs to the class of phenothiazines, which are characterized by a three-ring structure containing sulfur and nitrogen atoms. This compound is typically administered in its maleate salt form, which enhances its solubility and stability. Methotrimeprazine acts primarily as a dopamine antagonist, influencing neurotransmitter activity in the brain, which helps alleviate symptoms of psychosis and anxiety. It is also noted for its antihistaminic and anticholinergic effects, contributing to its sedative properties. The substance is usually available in oral and injectable forms, and its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes typical of many psychotropic medications. Side effects may include sedation, dry mouth, and potential extrapyramidal symptoms, which are common with antipsychotic drugs. As with any medication, it is essential to use methotrimeprazine maleate under medical supervision to manage dosage and monitor for adverse effects.
Formula:C19H24N2OS·C4H4O4
InChI:InChI=1/C19H24N2OS.C4H4O4/c1-14(12-20(2)3)13-21-16-7-5-6-8-18(16)23-19-10-9-15(22-4)11-17(19)21;5-3(6)1-2-4(7)8/h5-11,14H,12-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-;/m1./s1
SMILES:C(=C\C(O)=O)\C(O)=O.C([C@@H](CN(C)C)C)N1C=2C(SC=3C1=CC=CC3)=CC=C(OC)C2
Synonyms:
  • (2R)-3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine hydrogen (2Z)-but-2-enedioate
  • (2R)-3-(2-methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (2Z)-but-2-enedioate
  • (R)-3-(2-Methoxy-10H-phenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine maleate
  • 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,beta-trimethyl-, (betaR)-, (2Z)-2-butenedioate (1:1)
  • 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,β-trimethyl-, (R)-, (Z)-2-butenedioate (1:1)
  • 10H-Phenothiazine-10-propanamine, 2-methoxy-N,N,β-trimethyl-, (βR)-, (2Z)-2-butenedioate (1:1)
  • Levomepromazine hydrogen maleate
  • Levopromazine hydrogen maleate
  • Maleic acid, compd. with l-10-(3-dimethylamino-2-methylpropyl)-2-methoxyphenothiazine
  • Methoprazine
  • See more synonyms
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