CAS 71074-44-7

N~2~-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-N,N-dimethyl-L-glutamine

Description:

N~2~-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzoyl)-N,N-dimethyl-L-glutamine, commonly referred to by its CAS number 71074-44-7, is a synthetic compound that exhibits characteristics typical of complex organic molecules. It features a pteridine moiety, which is significant in biological systems, particularly in relation to folate metabolism. The presence of multiple functional groups, including amine and carboxylic acid functionalities, suggests that this compound may engage in hydrogen bonding and other intermolecular interactions, influencing its solubility and reactivity. The dimethyl and benzoyl substituents contribute to its structural complexity and may affect its pharmacokinetic properties. This compound is of interest in medicinal chemistry, particularly in the development of targeted therapies, as it may interact with specific biological pathways. Its stability, solubility, and biological activity would be influenced by its molecular structure, making it a candidate for further research in drug development and therapeutic applications.

Formula: C₂₂H₂₇N₉O₄

InChI: InChI=1/C22H27N9O4/c1-30(2)16(32)9-8-15(21(34)35)27-20(33)12-4-6-14(7-5-12)31(3)11-13-10-25-19-17(26-13)18(23)28-22(24)29-19/h4-7,10,15H,8-9,11H2,1-3H3,(H,27,33)(H,34,35)(H4,23,24,25,28,29)/t15-/m0/s1

SMILES: CN(C)C(=O)CC[C@@H](C(=O)O)NC(=O)c1ccc(cc1)N(C)Cc1cnc2c(c(N)[nH]c(=N)n2)n1

Methotrexate Impurity 1 HCl

CAS: 71074-44-7

Formula: C₂₂H₂₇N₉O₄·HCl

Color and Shape: Yellow Solid

Molecular weight: 481.52 36.46

Ref: 4Z-M-7028

Methotrexate Dimethylamide (>85%)

Controlled Product

CAS: 71074-44-7

Applications Methotrexate Dimethylamide is an impurity of Methotrexate (M260675) which is a folic acid antagonist. Used as a antineoplastic and antirheumatic.
References Freeman, M.V., J. Pharmacol. Exp. Ther., 122, 154 (1958), Weinblass, M.E., et al.: N. Engl. J. Med., 312, 818 (1985),

Formula: C₂₂H₂₇N₉O₄

Purity: >90%

Color and Shape: Neat

Molecular weight: 481.508

Ref: TR-M260695

Methotrexate dimethylamide

CAS: 71074-44-7

Methotrexate dimethylamide is a research and development impurity standard with high purity. It is a synthetic drug product that can be custom synthesized to meet the needs of the customer. Methotrexate dimethylamide has been used as an analytical standard for HPLC analysis and as a natural metabolite in metabolism studies. This compound is also known as 71074-44-7, CAS No. 71074-44-7, or Metabolite.

Formula: C₂₂H₂₇N₉O₄

Purity: Min. 95%

Molecular weight: 481.51 g/mol

Ref: 3D-IM182644

Methotrexate Dimethylamide

CAS: 71074-44-7

Formula: C₂₂H₂₇N₉O₄

Molecular weight: 481.52

Ref: ST-EA-CP-M12032