CAS 71079-19-1
:Timegadine
Description:
Timegadine, with the CAS number 71079-19-1, is a chemical compound that belongs to the class of antihistamines. It is primarily known for its use in the treatment of allergic conditions, such as hay fever and other allergic responses. Timegadine exhibits properties that allow it to block the action of histamine at H1 receptors, thereby alleviating symptoms like itching, sneezing, and runny nose. The compound is characterized by its ability to cross the blood-brain barrier, which may lead to central nervous system effects, including sedation. Its pharmacokinetics typically involve oral administration, with a metabolism that may vary among individuals. Timegadine's safety profile includes potential side effects common to antihistamines, such as drowsiness and dry mouth. As with any medication, it is essential to use Timegadine under medical supervision to manage dosage and monitor for adverse reactions. Overall, Timegadine represents a significant option in the pharmacological management of allergic symptoms.
Formula:C20H23N5S
InChI:InChI=1S/C20H23N5S/c1-14-13-18(16-9-5-6-10-17(16)22-14)24-19(25-20-21-11-12-26-20)23-15-7-3-2-4-8-15/h5-6,9-13,15H,2-4,7-8H2,1H3,(H2,21,22,23,24,25)
InChI key:InChIKey=SQVNITZYWXMWOG-UHFFFAOYSA-N
SMILES:N(=C(NC1=NC=CS1)NC2CCCCC2)C=3C4=C(N=C(C)C3)C=CC=C4
Synonyms:- 1-Cyclohexyl-2-(2-methylquinolin-4-yl)-3-(1,3-thiazol-2-yl)guanidine
- 2-Cyclohexyl-1-(2-Methylquinolin-4-Yl)-3-(1,3-Thiazol-2-Yl)Guanidine
- 275-184-0
- Guanidine, N-cyclohexyl-N′-(2-methyl-4-quinolinyl)-N′′-2-thiazolyl-
- N-Cyclohexyl-N′-(2-methyl-4-quinolinyl)-N′′-2-thiazolylguanidine
- Sr 1368
- Timegadine
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 2 products.
Timegadine
CAS:Timegadine is a competitive inhibitor of COX and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μMFormula:C20H23N5SPurity:98%Color and Shape:SolidMolecular weight:365.5
