CAS 71080-06-3

Guanidine, N′′-cyclohexyl-N-(2-methyl-4-quinolinyl)-N′-2-thiazolyl-, hydrochloride (1:1)

Description:

Guanidine, N′′-cyclohexyl-N-(2-methyl-4-quinolinyl)-N′-2-thiazolyl-, hydrochloride (1:1), with the CAS number 71080-06-3, is a chemical compound characterized by its guanidine core, which is modified with cyclohexyl, quinolinyl, and thiazolyl substituents. This compound typically appears as a hydrochloride salt, indicating that it is soluble in water and may exhibit ionic properties. The presence of the quinoline and thiazole moieties suggests potential biological activity, as these structures are often associated with pharmacological effects. Guanidine derivatives are known for their roles in various chemical reactions and biological processes, including their use as intermediates in the synthesis of pharmaceuticals. The compound's specific characteristics, such as melting point, solubility, and reactivity, would depend on its molecular structure and the interactions of its functional groups. Safety data and handling precautions should be consulted, as guanidine derivatives can exhibit toxicity and require careful management in laboratory settings.

Formula: C₂₀H₂₄ClN₅S

InChI: InChI=1/C20H23N5S.ClH/c1-14-13-18(16-9-5-6-10-17(16)22-14)24-19(25-20-21-11-12-26-20)23-15-7-3-2-4-8-15;/h5-6,9-13,15H,2-4,7-8H2,1H3,(H2,21,22,23,24,25);1H

InChI key: InChIKey=IWMWBGDREQGECL-UHFFFAOYSA-N

SMILES: N(=C(NC1=NC=CS1)NC2CCCCC2)C=3C4=C(N=C(C)C3)C=CC=C4.Cl

Synonyms:

• 3-Cyclohexyl-1-(2-Methyl-4-Quinolyl)-2-Thiazol-2-Yl-Guanidine Hydrochloride
• Guanidine, N-cyclohexyl-N′-(2-methyl-4-quinolinyl)-N′′-2-thiazolyl-, monohydrochloride
• Guanidine, N′′-cyclohexyl-N-(2-methyl-4-quinolinyl)-N′-2-thiazolyl-, hydrochloride (1:1)
• N-Cyclohexyl-N'-(2-methyl-4-quinolineyl)-N''-thiazol-2-ylguanidinemonohydrochloride
• N-cyclohexyl-N'-(2-methyl-4-quinolineyl)-N''-thiazol-2-ylguanidine monohydrochloride

Timegadine hydrochloride

CAS: 71080-06-3

Timegadine hydrochloride (SR1368 hydrochloride) is the hydrochloride salt form of Timegadine. It is an orally active inhibitor of COX and lipo-oxygenase, effectively suppressing COX in rabbit platelets and rat brain with IC50 values of 5 nM and 20 μM, respectively, and inhibiting lipo-oxygenase in horse and rabbit platelets with an IC50 of 100 μM. Timegadine hydrochloride also exhibits anti-arthritis activity.

Formula: C₂₀H₂₄ClN₅S

Color and Shape: Solid

Molecular weight: 401.96

Ref: TM-T203602