CAS 71109-09-6

Vedaprofen

Description:

Vedaprofen is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, compounds involved in inflammation and pain signaling. Vedaprofen is often utilized in veterinary medicine, particularly for the treatment of pain and inflammation in animals, such as dogs and horses. The substance is typically administered orally and is known for its relatively favorable safety profile compared to other NSAIDs. Its chemical structure includes a propionic acid derivative, which contributes to its pharmacological effects. Vedaprofen is also noted for its moderate potency and duration of action, making it suitable for managing various inflammatory conditions. As with all medications, potential side effects may include gastrointestinal disturbances and renal effects, necessitating careful monitoring during use. Overall, Vedaprofen serves as an important therapeutic option in the management of pain and inflammation in veterinary practice.

Formula: C₁₉H₂₂O₂

InChI: InChI=1S/C19H22O2/c1-13(19(20)21)15-11-12-16(14-7-3-2-4-8-14)18-10-6-5-9-17(15)18/h5-6,9-14H,2-4,7-8H2,1H3,(H,20,21)

InChI key: InChIKey=VZUGVMQFWFVFBX-UHFFFAOYSA-N

SMILES: C(C(O)=O)(C)C=1C2=C(C(=CC1)C3CCCCC3)C=CC=C2

Synonyms:

• (+-)-4-Cyclohexyl-alpha-methyl-1-naphthaleneacetic acid
• 1-Naphthaleneacetic acid, 4-cyclohexyl-alpha-methyl-, (+-)-
• 1-Naphthaleneacetic acid, 4-cyclohexyl-α-methyl-
• 2-(1-Cyclohexylnaphthalen-4-yl)propanoic acid
• 2-(4-Cyclohexylnaphthalen-1-Yl)Propanoic Acid
• 4-Cyclohexyl-alpha-methylnaphthalene-1-acetic acid
• 4-Cyclohexyl-Α-Methylnaphthalene-1-Acetic Acid
• 4-Cyclohexyl-α-methyl-1-naphthaleneacetic acid
• Cerm 10202
• Pm 150
• Quadrisol
• Unii-Okx88Eo7Oi
• Vedaprofen [USAN:INN:BAN]

VEDAPROFEN CRS

CAS: 71109-09-6

VEDAPROFEN CRS

Formula: C₁₉H₂₂O₂

Color and Shape: Powder.

Molecular weight: 282.3768

Ref: 41-Y0001093

1-Naphthaleneaceticacid, 4-cyclohexyl-a-methyl-

CAS: 71109-09-6

Formula: C₁₉H₂₂O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 282.3768

Ref: IN-DA0060D5

Vedaprofen

CAS: 71109-09-6

Vedaprofen (PM 150) is a COX-1 inhibitor with anti-inflammatory effects, blocking E. coli clamp at IC50 222 μM, Ki 131 μM.

Formula: C₁₉H₂₂O₂

Purity: 99.24% - 99.70%

Color and Shape: Solid

Molecular weight: 282.38

Ref: TM-T36683

Vedaprofen

CAS: 71109-09-6

Vedaprofen

Purity: ≥98%

Molecular weight: 282.38g/mol

Ref: 54-BUP15180

Vedaprofen 100 µg/mL in Acetonitrile

CAS: 71109-09-6

Formula: C₁₉H₂₂O₂

Color and Shape: Single Solution

Molecular weight: 282.38

Ref: 04-A17906000AL-100

Vedaprofen

Controlled Product

CAS: 71109-09-6

Formula: C₁₉H₂₂O₂

Color and Shape: Neat

Molecular weight: 282.38

Ref: 04-C17906000

Vedaprofen

CAS: 71109-09-6

Applications Propionic acid type non-steroidal anti-inflammatory drug (NSAID).
References Mitchell, J., et al.: Biochem. Pharmacol., 50, 1535 (1995), Haak, T., et al.: Clin. Exp. Rheumatol., 14(6), 633 (1996), Lees, P., et al.: J. Vet. Pharmacol. Ther., 22, 96 (1999), Hawkey, C., et al.: Arthritis Rheum., 43, 370 (2000),

Formula: C₁₉H₂₂O₂

Color and Shape: White To Brown

Molecular weight: 282.38

Ref: TR-V105300

Vedaprofen

CAS: 71109-09-6

Purity: 98%

Molecular weight: 282.3829956

Ref: 10-F610136

Vedaprofen

CAS: 71109-09-6

Vedaprofen is a nonsteroidal anti-inflammatory drug that belongs to the class of drugs known as NSAIDs. It inhibits the activity of the enzyme cyclooxygenase (COX), which causes inflammation and pain. Vedaprofen has been shown to be effective in treating bowel disease, inflammatory bowel disease, and autoimmune diseases, such as arthritis. Vedaprofen also has antimicrobial properties, inhibiting bacterial growth by binding to the COX enzyme in the cell membrane. The α subunit is one of the effector proteins for COX-1 and COX-2, and vedaprofen binds to this protein preventing its activation. This inhibitory effect on COX-1 and COX-2 leads to a reduction in production of prostaglandins (PGs) that are responsible for inflammatory responses. Vedaprofen may be administered orally or intravenously depending on the severity of symptoms. The oral route is preferred because it does not require

Formula: C₁₉H₂₂O₂

Purity: Min. 95%

Molecular weight: 282.38 g/mol

Ref: 3D-FV28675