CAS 71116-82-0

Tiaprost

Description:

Tiaprost is a synthetic compound classified as a prostaglandin analog, primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. It functions by increasing the outflow of aqueous humor, thereby reducing intraocular pressure. The chemical structure of Tiaprost includes a carboxylic acid group and a cyclopentane ring, which are characteristic of prostaglandin derivatives. Its mechanism of action involves binding to specific prostaglandin receptors in the eye, leading to enhanced drainage of fluid. Tiaprost is typically administered as an eye drop solution, and its pharmacokinetics include rapid absorption and a relatively short half-life, necessitating regular dosing for effective management of eye pressure. Additionally, it may cause side effects such as conjunctival hyperemia, eye irritation, and changes in eyelash growth. As with any medication, it is essential to use Tiaprost under the guidance of a healthcare professional to ensure safety and efficacy.

Formula: C₂₀H₂₈O₆S

InChI: InChI=1S/C20H28O6S/c21-14(12-26-15-9-10-27-13-15)7-8-17-16(18(22)11-19(17)23)5-3-1-2-4-6-20(24)25/h1,3,7-10,13-14,16-19,21-23H,2,4-6,11-12H2,(H,24,25)

InChI key: InChIKey=FYBFDIIAPRHIQS-UHFFFAOYSA-N

SMILES: C(C=CCCCC(O)=O)C1C(C=CC(COC=2C=CSC2)O)C(O)CC1O

Synonyms:

• (5E)-7-{3,5-dihydroxy-2-[(1E)-3-hydroxy-4-(thiophen-3-yloxy)but-1-en-1-yl]cyclopentyl}hept-5-enoic acid
• (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-hydroxy-4-(thiophen-3-yloxy)but-1-en-1-yl]cyclopentyl}hept-5-enoic acid
• 5-Heptenoic acid, 7-[3,5-dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-buten-1-yl]cyclopentyl]-
• 5-Heptenoic acid, 7-[3,5-dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-butenyl]cyclopentyl]-
• 7-[3,5-Dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-buten-1-yl]cyclopentyl]-5-heptenoic acid
• 7-[3,5-Dihydroxy-2-[3-hydroxy-4-(3-thienyloxy)-1-butenyl]cyclopentyl]-5-heptenoic Acid
• Iliren
• Tiaprost

Tiaprost

CAS: 71116-82-0

Tiaprost is a analog of prostaglandin F2α .

Formula: C₂₀H₂₈O₆S

Purity: 98%

Color and Shape: Solid

Molecular weight: 396.5

Ref: TM-T17092

Tiaprost

CAS: 71116-82-0

Tiaprost is a synthetic analogue of prostaglandin F2α that has been used in animal health and fertility. This drug stimulates follicular growth and ovulation in cows and heifers, as well as increases estradiol benzoate (EB) levels in the blood. Tiaprost is also used to treat intrauterine infections caused by bacteria, such as E. coli, or protozoa, such as Tritrichomonas foetus. Tiaprost has been shown to be clinically relevant for the treatment of human infertility due to its ability to stimulate ovulation in women with polycystic ovary syndrome (PCOS).

Formula: C₂₀H₂₈O₆S

Purity: Min. 95%

Molecular weight: 396.5 g/mol

Ref: 3D-WCA11682