CAS 71140-51-7
:(R)-(-)-mephenytoin
Description:
(R)-(-)-Mephenytoin is a pharmaceutical compound primarily used as an anticonvulsant in the treatment of epilepsy. It is a chiral molecule, meaning it has a specific three-dimensional arrangement that influences its biological activity. The compound features a phenyl group and an ethyl side chain, contributing to its lipophilicity and ability to cross the blood-brain barrier. As a member of the hydantoin class of drugs, it functions by stabilizing neuronal membranes and reducing the excitability of neurons. The stereochemistry of (R)-(-)-mephenytoin is crucial for its therapeutic effects, as different enantiomers can exhibit varying pharmacological properties. The substance is typically administered orally and is metabolized in the liver, with its pharmacokinetics influenced by genetic factors and interactions with other medications. Safety and efficacy profiles are well-documented, but potential side effects may include dizziness, drowsiness, and gastrointestinal disturbances. Overall, (R)-(-)-mephenytoin exemplifies the importance of stereochemistry in drug design and therapeutic application.
Formula:C12H14N2O2
InChI:InChI=1/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m1/s1
SMILES:CC[C@@]1(c2ccccc2)C(=O)N(C)C(=N1)O
Synonyms:- (5R)-5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
- (R)-Mephenytoin
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Found 6 products.
(R)-Mephenytoin
CAS:<p>(R)-Mephenytoin ((–)-Mephenytoin) is the the R-enantiomer of Mephenytoin which is an anticonvulsant agent.</p>Formula:C12H14N2O2Purity:99.95%Color and Shape:SolidMolecular weight:218.25(R)-Mephenytoin
CAS:Controlled Product<p>Applications An anticonvulsant agent.<br>References Shimada, et al.: Anal. Biochem., 147, 174 (1975), Dzhagatspanyan. IA., et al.: Pharm. Chem. J., 25, 181 (1991),<br></p>Formula:C12H14N2O2Color and Shape:NeatMolecular weight:218.25
