CAS 71293-22-6

5-Chloro-4-hydroxy-1,3-benzenedisulfonyl Dichloride

Controlled Product

CAS: 71293-22-6

Applications 5-Chloro-4-hydroxy-1,3-benzenedisulfonyl Dichloride is an intermediate used in the synthesis of Diclofenamide-13C6 (D436532), which is a labelled Diclofenamide, a potent carbonic anhydrase inhibitor. Diclofenamide may provide a therapeutic strategy in the inhibition of the human cytosolic isoforms I and II and transmembrane tumor-associated isoenzymes IX and XII. Diclofenamide has been shown to be is effective in the prevention of episodic weakness in both hypokalemic periodic paralysis (HypoPP) and potassium-sensitive periodic paralysis (PSPP).
References Brzozowski, Z. et al.: Eur. J. Med. Chem., 46, 3656 (2010); Tawil, R. et al.: Ann. Neurol., 47, 46 (2000); Casey, J. et al.: J. Med. Chem., 47, 2337 (2004);

Formula: C₆H₃Cl₃O₅S₂

Color and Shape: Neat

Molecular weight: 331.53

Ref: TR-C360337