CAS 71293-62-4

5-Trifluoromethyloxindole

Description:

5-Trifluoromethyloxindole is an organic compound characterized by the presence of a trifluoromethyl group and an oxindole structure. The trifluoromethyl group (-CF3) is known for its electron-withdrawing properties, which can significantly influence the reactivity and stability of the compound. Oxindoles are a class of compounds derived from indole, featuring a carbonyl group adjacent to the nitrogen atom, which contributes to their biological activity. This compound is typically a solid at room temperature and is soluble in organic solvents. It is of interest in medicinal chemistry due to its potential applications in drug development, particularly in the synthesis of pharmaceuticals and agrochemicals. The presence of the trifluoromethyl group can enhance lipophilicity and metabolic stability, making it a valuable moiety in the design of bioactive molecules. As with many fluorinated compounds, handling requires caution due to potential environmental and health impacts. Overall, 5-Trifluoromethyloxindole exemplifies the intersection of organic synthesis and medicinal chemistry, showcasing the importance of functional group manipulation in compound design.

Formula: C₉H₆F₃NO

InChI: InChI=1/C9H6F3NO/c10-9(11,12)6-1-2-7-5(3-6)4-8(14)13-7/h1-3H,4H2,(H,13,14)

SMILES: c1cc2c(cc1C(F)(F)F)CC(=O)N2

Synonyms:

• 5-(trifluoromethyl)-1,3-dihydro-2H-indol-2-one
• 5-Trifluoromethyl-2-Oxindole
• 5-(Trifluoromethyl)oxindole 97%
• 5-(TRIFLUOROMETHYL)OXINDOLE
• 5-(Trifluoromethyl)oxindole97%
• 5-(TRIFLUOROMETHYL)OXINDOLE ,98%
• 5-(Trifluoromethyl)-2-oxoindole

5-Trifluoromethyloxindole

CAS: 71293-62-4

Formula: C₉H₆F₃NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 201.1452

Ref: IN-DA0069H2

5-(Trifluoromethyl)-2-oxindole

CAS: 71293-62-4

5-(Trifluoromethyl)-2-oxindole

Formula: C₉H₆F₃NO

Purity: 98%

Color and Shape: brown solid

Molecular weight: 201.15g/mol

Ref: 54-PC1742

5-(Trifluoromethyl)indolin-2-one

CAS: 71293-62-4

Formula: C₉H₆F₃NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 201.148

Ref: 10-F210438

5-(Trifluoromethyl)indolin-2-one

Controlled Product

CAS: 71293-62-4

Applications 5-(Trifluoromethyl)indolin-2-one is a useful reagent for the preparation of 3-Chloro-α-carbolines.
References Tian, S., et al.: Synlett, 29, 949 (2018)

Formula: C₉H₆NOF₃

Color and Shape: Neat

Molecular weight: 201.15

Ref: TR-T899643