CAS 71352-89-1

N-(2,6-Dimethylphenyl)-3-methyl-2-butenamide

Controlled Product

CAS: 71352-89-1

Applications N-(2,6-Dimethylphenyl)-3-methyl-2-butenamide is an intermediate in the synthesis of rac-trans-N-(2,6-Dimethylphenyl)-4-methyl-1-(2-methylphenyl)-5-oxo-3-propylimidazolidine-2-carboxamide (D480822), the trans-isomer of N-(2,6-Dimethylphenyl)-4-methyl-1-(2-methylphenyl)-5-oxo-3-propylimidazolidine-2-carboxamide, an impurity of Prilocaine (Prilocaine Hydrochloride P725000). Prilocaine is a local anesthetic of the amino amide type and is often used in dentistry. Prilocaine is also often combined with lidocaine as a preparation for dermal anesthesia (lidocaine/prilocaine or EMLA) towards the treatment of conditions like paresthesia.
References Caliaro, G., et al.: J. Pharm. Biomed. Anal., 26, 427 (2001), Ulmeanu, S., et al.: Pharm. Res., 20, 1317 (2003),

Formula: C₁₃H₁₇NO

Color and Shape: Neat

Molecular weight: 203.28

Ref: TR-D465630