CAS 71395-14-7

Tocainide hydrochloride

Description:

Tocainide hydrochloride is a pharmaceutical compound primarily used as an antiarrhythmic agent, particularly for the treatment of ventricular arrhythmias. It is a member of the class 1B antiarrhythmics, which work by stabilizing the cardiac cell membrane and reducing excitability. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Tocainide hydrochloride is characterized by its ability to block sodium channels, thereby influencing cardiac action potentials and conduction. Its pharmacokinetics involve oral bioavailability, with metabolism primarily occurring in the liver. The compound may exhibit side effects typical of antiarrhythmics, including potential neurological effects, and requires careful monitoring of plasma levels to avoid toxicity. Due to its specific action on cardiac tissues, tocainide hydrochloride is often prescribed when other antiarrhythmic medications are ineffective or contraindicated. As with all medications, it is essential to consider patient-specific factors and potential drug interactions when prescribing tocainide hydrochloride.

Formula: C₁₁H₁₆N₂O

InChI: InChI=1/C11H16N2O.ClH/c1-7-5-4-6-8(2)10(7)13-11(14)9(3)12;/h4-6,9H,12H2,1-3H3,(H,13,14);1H

InChI key: InChIKey=AMZACPWEJDQXGW-UHFFFAOYSA-N

SMILES: N(C(C(C)N)=O)C1=C(C)C=CC=C1C.Cl

Synonyms:

• (1)-2-Amino-N-(2,6-dimethylphenyl)propionamide hydrochloride
• 2-Amino-2',6'-propionoxylidide hydrochloride
• 2-Amino-2′,6′-propionoxylidide hydrochloride
• Propanamide, 2-amino-N-(2,6-dimethylphenyl)-, hydrochloride (1:1)
• Propanamide, 2-amino-N-(2,6-dimethylphenyl)-, monohydrochloride
• Taquidil
• Tocainide (+-)-form hydrochloride
• Tocainide HCl
• Tocainide hydrochloride
• Tonocard
• Unii-2K7I38Ckn5
• Xylotocan
• (±)-2-amino-N-(2,6-dimethylphenyl)propionamide hydrochloride
• (±)-Form hydrochloride
• rac-(R*)-2-Amino-N-(2,6-dimethylphenyl)propanamide·hydrochloride

Tocainide hydrochloride

CAS: 71395-14-7

Formula: C₁₁H₁₆N₂O·HCl

Molecular weight: 228.72

Ref: 7W-GL2205

Tocainide

CAS: 71395-14-7

Formula: C₁₁H₁₆N₂O

Molecular weight: 192.26

Ref: 4Z-T-169001

Tocainide HCl

CAS: 71395-14-7

Sodium channel blocker

Formula: C₁₁H₁₇ClN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 228.72 g/mol

Ref: 3D-FA61493

Tocainide HCl - Bio-X ™

CAS: 71395-14-7

Tocainide is a class 1b antiarrhythmic agent that is used in the treatment of ventricular arrhythmias. This drug acts on sodium channels to decrease the excitability of myocardial cells. This drug also prevents the depolarization of cardiac muscle cells and prolongs their refractory period.

Formula: C₁₁H₁₇ClN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 228.72 g/mol

Ref: 3D-BT164480

T525452

Controlled Product

CAS: 71395-14-7

Formula: C₁₁H₁₂D₄N₂O•HCl

Color and Shape: Neat

Molecular weight: 196.29 + (36.46)

Ref: TR-T525452

Tocainide Hydrochloride

Controlled Product

CAS: 71395-14-7

Applications Tocainide Hydrochloride is used as an anti-arrythmic drug as myocardial depressants.
References Courtney, K. et al. J. Molec. Cell. Cardiol., 12, 1273 (1980); Kwok, D. et al.: Res. Comm. Chem. Path. Pharm., 67, 395 (1990);

Formula: C₁₁H₁₆N₂O·ClH

Color and Shape: Neat

Molecular weight: 228.72

Ref: TR-T525450

Taquidil

CAS: 71395-14-7

Tocainide hydrochloride: oral antiarrhythmic, sodium channel blocker, akin to lidocaine.

Formula: C₁₁H₁₇ClN₂O

Color and Shape: Solid

Molecular weight: 228.718

Ref: TM-T13177

Tocainide Hydrochloride

CAS: 71395-14-7

Color and Shape: Neat

Ref: 61-FOR3323.00