CAS 71432-55-8

1,1-Dimethylethyl N,N′-bis(1-methylethyl)carbamimidate

Description:

1,1-Dimethylethyl N,N′-bis(1-methylethyl)carbamimidate, with the CAS number 71432-55-8, is a chemical compound characterized by its unique structure, which includes a carbamimidate functional group. This compound features two tert-butyl groups attached to the nitrogen atoms, contributing to its steric bulk and potentially influencing its reactivity and solubility. Typically, carbamimidates are known for their role as intermediates in organic synthesis and can exhibit properties such as being basic and nucleophilic. The presence of the dimethyl and bis(1-methylethyl) substituents suggests that this compound may have applications in various chemical reactions, including those involving nucleophilic attack or as a ligand in coordination chemistry. Additionally, the steric hindrance provided by the bulky groups may affect its interaction with other molecules, making it of interest in studies related to catalysis or material science. As with many chemical substances, safety data and handling precautions should be considered when working with this compound in a laboratory setting.

Formula: C₁₁H₂₄N₂O

InChI: InChI=1S/C11H24N2O/c1-8(2)12-10(13-9(3)4)14-11(5,6)7/h8-9H,1-7H3,(H,12,13)

InChI key: InChIKey=FESDUDPSRMWIDL-UHFFFAOYSA-N

SMILES: O(C(=NC(C)C)NC(C)C)C(C)(C)C

Synonyms:

• 1,1-Dimethylethyl N,N′-bis(1-methylethyl)carbamimidate
• 2-Tert-Butyl-1,3-Diisopropylisourea
• 2-tert-Butyl-1,3-diisopropylpseudourea
• CarbaMiMidic acid, N,N'-bis(1-Methylethyl)-, 1,1-diMethylethyl ester
• N,N′-Diisopropyl-O-tert-butylisourea
• O-tert-Butyl-N,N'-diisopropylisourea
• tert-Butyl N,N'-diisopropylcarbaMiMidate
• tert-Butyl N,N′-dipropan-2-ylcarbamimidate

O-tert-Butyl-N,N'-diisopropylisourea

CAS: 71432-55-8

Formula: C₁₁H₂₄N₂O

Purity: >95.0%(T)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 200.33

Ref: 3B-B4178

Tert-Butyl N,N'-diisopropylcarbamimidate

CAS: 71432-55-8

Purity: 95.0%

Color and Shape: Liquid

Molecular weight: 200.3260040283203

Ref: 10-F210414

2-tert-Butyl-1,3-diisopropylisourea

CAS: 71432-55-8

Formula: C₁₁H₂₄N₂O

Purity: 95%

Color and Shape: Liquid

Molecular weight: 200.3211

Ref: IN-DA0035ZS

O-Tert-Butyl-N,N-Diisopropylisourea

CAS: 71432-55-8

O-Tert-Butyl-N,N-Diisopropylisourea

Purity: 95%

Molecular weight: 200.33g/mol

Ref: 54-OR1030582

tert-Butyl N,N'-diisopropylcarbamimidate

CAS: 71432-55-8

tert-Butyl N,N'-diisopropylcarbamimidate

Formula: C₁₁H₂₄N₂O

Purity: 95%

Color and Shape: colourless liquid

Molecular weight: 200.32g/mol

Ref: 54-OR955440

2-tert-Butyl-1,3-diisopropylisourea

Controlled Product

CAS: 71432-55-8

Applications 2-tert-Butyl-1,3-diisopropylisourea is a useful synthetic intermediate in the synthesis of 5-Oxo Atorvastatin tert-Butyl Ester (O847160) which is a Boc-protected derivative of Atorvastatin (A791750, Ca Salt). 2-tert-Butyl-1,3-diisopropylisourea is also used as a reagent in the total synthesis of Citrafungin A which is an antifungal natural product.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000); Calo, F., et al.: J. Org. Chem., 73, 9692 (2008)

Formula: C₁₁H₂₄N₂O

Color and Shape: Neat

Molecular weight: 200.32

Ref: TR-B692565

2-tert-Butyl-1,3-diisopropylisourea

CAS: 71432-55-8

2-tert-Butyl-1,3-diisopropylisourea is a chemical compound that is an inhibitor of the hepatitis C virus NS5B polymerase. The compound has been shown to inhibit viral replication in cell culture and to protect against liver damage in mice. 2-tert-Butyl-1,3-diisopropylisourea inhibits the activity of the hepatitis C virus by binding to a region of the enzyme's active site called the "pharmacophore". This region is located at the end of a long, flexible arm that extends from the main body of the enzyme. This binding prevents formation of a critical thiol group linkage required for RNA synthesis. The compound can be used as an antiviral agent or as a potential therapy for chronic hepatitis B and C, which are viral diseases that lead to liver disease. 2-tert-Butyl-1,3-diisopropylisourea

Formula: C₁₁H₂₄N₂O

Purity: Min. 95%

Color and Shape: Colorless Clear Liquid

Molecular weight: 200.32 g/mol

Ref: 3D-FB53703