CAS 7146-68-1

4-[(4-chlorophenyl)sulfonyl]aniline

Description:

4-[(4-Chlorophenyl)sulfonyl]aniline, also known by its CAS number 7146-68-1, is an organic compound characterized by the presence of both an aniline group and a sulfonyl moiety. This compound features a sulfonyl group (-SO2-) attached to a phenyl ring that is further substituted with a chlorine atom, making it a chlorinated aromatic sulfonamide. It typically appears as a solid at room temperature and is soluble in organic solvents, though its solubility in water is limited. The presence of the sulfonyl group contributes to its potential as a sulfonamide, which can exhibit various biological activities, including antimicrobial properties. The chlorine substituent can influence the compound's reactivity and interaction with biological systems. Due to its structural characteristics, 4-[(4-chlorophenyl)sulfonyl]aniline may be of interest in pharmaceutical research and development, particularly in the synthesis of new compounds with targeted biological activities. Safety data should be consulted for handling and usage, as with any chemical substance.

Formula: C₁₂H₁₀ClNO₂S

InChI: InChI=1S/C12H10ClNO2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,14H2

InChI key: InChIKey=RWIUBJDOESNTFZ-UHFFFAOYSA-N

SMILES: S(=O)(=O)(C1=CC=C(Cl)C=C1)C2=CC=C(N)C=C2

Synonyms:

• 4-(4-Chlorobenzenesulfonyl)phenylamine
• 4-Amino-4′-chlorodiphenyl sulfone
• 4-Aminophenyl 4-chlorophenyl sulfone
• 4-[(4-Chlorophenyl)sulfonyl]benzenamine
• Aniline, p-[(p-chlorophenyl)sulfonyl]-
• Benzenamine, 4-[(4-Chlorophenyl)Sulfonyl]-
• NSC 23812
• NSC 51990
• p-(p-Chlorophenylsulfonyl)aniline
• p-Aminophenyl p-chlorophenyl sulfone
• 4-(4-chlorophenyl)sulfonylaniline
• Dapsone Aniline Chlorophenyl Impurity
• p-[(p-Chlorophenyl)sulfonyl]aniline
• Dapsone Impurity 5
• Dapsone Impurity 2

Chloro Dapsone (4-[(4-Chlorophenyl)sulfonyl]aniline)

CAS: 7146-68-1

Other aromatic organo-sulfur compounds (excluding pesticides)

Formula: C₁₂H₁₀ClNO₂S

Color and Shape: Off-White Powder

Molecular weight: 267.01208

Ref: 45-1A10520

4-(4-Chloro-benzenesulfonyl)phenylamine

CAS: 7146-68-1

Formula: C₁₂H₁₀ClNO₂S

Purity: 97%

Color and Shape: Solid

Molecular weight: 267.7313

Ref: IN-DA0066TD

Dapsone EP Impurity E

CAS: 7146-68-1

Formula: C₁₂H₁₀ClNO₂S

Molecular weight: 267.73

Ref: 4Z-D-016

4-((4-Chlorophenyl)sulfonyl)aniline

CAS: 7146-68-1

4-((4-Chlorophenyl)sulfonyl)aniline

Purity: ≥97%

Molecular weight: 267.73g/mol

Ref: 54-OR1043242

4-((4-Chlorophenyl)sulfonyl)aniline

CAS: 7146-68-1

Formula: C₁₂H₁₀ClNO₂S

Purity: 97%

Molecular weight: 267.73

Ref: 10-F320799

4-Amino-4'-chlorodiphenyl Sulfone

Controlled Product

CAS: 7146-68-1

Applications 4-Amino-4'-chlorodiphenyl sulfone is a substituted 4-aminodiphenylsulfone as Escherichia coli dihydropteroate synthase inhibitor.
References Lopez de Compadre, R.L., et al.: J. Med. Chem., 31, 2315 (1988),

Formula: C₁₂H₁₀ClNO₂S

Color and Shape: Off-White To Light Yellow

Molecular weight: 267.73

Ref: TR-A603775

Dapsone EP Impurity E

CAS: 7146-68-1

Formula: C₁₂H₁₀ClNO₂S

Molecular weight: 267.7

Ref: ST-EA-CP-D10004

4-((4-Chlorophenyl)sulfonyl)aniline

CAS: 7146-68-1

4-((4-Chlorophenyl)sulfonyl)aniline is a synthetic sulfone that is used as an antileprosy agent. It has been shown to inhibit the growth of Mycobacterium leprae and Mycobacterium tuberculosis. 4-((4-Chlorophenyl)sulfonyl)aniline also has anti-inflammatory properties, which make it useful for the treatment of various skin diseases such as eczema, psoriasis, and atopic dermatitis. The chemical structure of 4-((4-chlorophenyl)sulfonyl)aniline is similar to that of dapsone, but with a substituted phenyl group on the sulfur atom. This substitution leads to decreased solubility in water and increased solubility in organic solvents such as acetone and ethanol.

Formula: C₁₂H₁₀ClNO₂S

Purity: Min. 95%

Molecular weight: 267.73 g/mol

Ref: 3D-HAA14668