CAS 714966-38-8

Prosta-5,13-dien-1-amide,9,11,15-trihydroxy-N-(2-hydroxyethyl)-, (5Z,9a,11b,13E,15S)- (9CI)

Description:

Prosta-5,13-dien-1-amide,9,11,15-trihydroxy-N-(2-hydroxyethyl)-, commonly referred to by its CAS number 714966-38-8, is a synthetic compound that belongs to the class of prostaglandin analogs. This substance is characterized by its complex molecular structure, which includes multiple hydroxyl groups and an amide functional group, contributing to its biological activity. The presence of the trihydroxy groups suggests potential interactions with biological systems, particularly in modulating inflammatory responses and other physiological processes. The specific stereochemistry indicated by the (5Z,9a,11b,13E,15S) notation highlights the compound's three-dimensional arrangement, which is crucial for its interaction with biological targets. Prosta-5,13-dien-1-amide is often studied for its pharmacological properties, including its potential effects on vascular function and cell signaling pathways. As with many prostaglandin derivatives, it may exhibit a range of biological activities, making it of interest in medicinal chemistry and therapeutic applications.

Formula: C₂₂H₃₉NO₅

Synonyms:

• 11BETA-PROSTAGLANDIN F2ALPHA ETHANOLAMIDE
• 11BETA-PGF2ALPHA-EA
• N-(2-HYDROXYETHYL)-9ALPHA, 11BETA, 15S-TRIHYDROXY-PROSTA-5Z, 13E-DIEN-1-AMIDE

11β-Prostaglandin F2α Ethanolamide

CAS: 714966-38-8

11β-Prostaglandin F2αethanolamide (11β-PGF2α-EA), posited as the hepatic metabolite derived from PGD2-EA during COX-2 metabolism of AEA—an endogenous cannabinoid present in brain, liver, and various mammalian tissues—is synthesized directly from AEA via COX-2 and specific prostaglandin synthase, leading to ethanolamide versions of classical prostaglandins. Additionally, PGD2-EA formation occurs in activated RAW 264.7 cells upon AEA treatment.

Formula: C₂₂H₃₉NO₅

Color and Shape: Solid

Molecular weight: 397.6

Ref: TM-T84655