CAS 7154-66-7

2-Bromobenzoyl chloride

Description:

2-Bromobenzoyl chloride, with the CAS number 7154-66-7, is an organic compound that belongs to the class of acyl chlorides. It features a benzoyl group substituted with a bromine atom at the ortho position relative to the carbonyl group. This compound is typically a colorless to pale yellow liquid with a pungent odor, characteristic of acyl chlorides. It is highly reactive, particularly with water, leading to the formation of 2-bromobenzoic acid and hydrochloric acid upon hydrolysis. 2-Bromobenzoyl chloride is soluble in organic solvents such as dichloromethane and ether but is insoluble in water due to its hydrophobic nature. It is commonly used as an intermediate in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals. Safety precautions are essential when handling this compound, as it can cause severe irritation to the skin, eyes, and respiratory tract, and it is classified as a hazardous material. Proper storage in a cool, dry place away from moisture is also recommended to maintain its stability.

Formula: C₇H₄BrClO

InChI: InChI=1/C7H4BrClO/c8-6-4-2-1-3-5(6)7(9)10/h1-4H

InChI key: InChIKey=NZCKTGCKFJDGFD-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C1=C(Br)C=CC=C1

Synonyms:

• 2-Bromobenzene-1-carbonyl chloride
• 2-Bromobenzoic acid chloride
• 4-Chloro-3-Nitrobenzyl Chloride
• Benzoyl chloride, 2-bromo-
• Benzoyl chloride, o-bromo-
• NSC 73706
• o-Bromobenzoyl chloride
• 2-Bromobenzoyl chloride
• o-bromo-benzoylchlorid
• AKOS 90922
• AKOS BBS-00004081

2-Bromobenzoyl chloride, 98%

CAS: 7154-66-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₄BrClO

Purity: 98%

Color and Shape: Clear colorless to yellow to orange, Liquid

Molecular weight: 219.47

Ref: 02-A14520

2-Bromobenzoyl chloride

CAS: 7154-66-7

2-Bromobenzoyl chloride

Formula: C₇H₄BrClO

Purity: 98%

Color and Shape: clear. yellow to orange low-melting solid/liquid liquid

Molecular weight: 219.46306g/mol

Ref: 54-OR26841

2-Bromobenzoyl Chloride

CAS: 7154-66-7

Formula: C₇H₄BrClO

Purity: >98.0%(GC)(T)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 219.46

Ref: 3B-B1238

2-Bromobenzoyl chloride

CAS: 7154-66-7

2-Bromobenzoyl chloride (2BB) is an aromatic hydrocarbon that can be used to synthesize a variety of organic compounds. 2BB has been shown to have cytotoxic activity in vitro, but it is not yet known what the mechanism of action is. In addition, 2BB binds to DNA and RNA, and it has been used as a reagent for the synthesis of phenyl groups. The compound also reacts with copper or carbonate ions to form bromocarbenes or chlorocarbenes respectively. 2BB is also used for the Friedel-Crafts reaction, Suzuki coupling reaction, and acylation reactions.

Formula: C₇H₄BrClO

Purity: Min. 95%

Molecular weight: 219.46 g/mol

Ref: 3D-FB159681

2-Bromobenzoyl chloride

CAS: 7154-66-7

Formula: C₇H₄BrClO

Purity: 98.0%

Color and Shape: Solid, Low Melting Solid

Molecular weight: 219.46

Ref: 10-F001051

2-Bromobenzoyl Chloride

Controlled Product

CAS: 7154-66-7

Applications 2-Bromobenzoyl chloride is used in synthetic chemistry as an acylating agent. 2-Bromobenzoyl chloride is also used as a reagent to synthesize fluorazone, a heteroaromatic compound that exhibits antidiabetic, psychostimulant and anticancer activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Calvert, M. & Sperry, J.: J. Hetero. Chem., 51, 282 (2014); Takeda, Y., et al.: Tetrahedron Lett., 45, 3481 (2004); Wang, R., et al.: J. Lumin., 154, 8 (2014); Wang, S., et al.: Eur. J. Org. Chem., 2013, 7631 (2013)

Formula: C₇H₄BrClO

Color and Shape: Neat

Molecular weight: 219.46

Ref: TR-B680380