CAS 71620-89-8

Reboxetine

Description:

Reboxetine is a selective norepinephrine reuptake inhibitor (NRI) primarily used as an antidepressant. It is characterized by its ability to enhance norepinephrine levels in the synaptic cleft by inhibiting its reabsorption into presynaptic neurons. This mechanism is thought to contribute to its antidepressant effects, making it particularly effective in treating major depressive disorder. Reboxetine is typically administered in oral form and has a relatively long half-life, allowing for once-daily dosing. Its chemical structure includes a phenoxyphenyl moiety, which is crucial for its pharmacological activity. The substance is known for its favorable side effect profile compared to some other antidepressants, with a lower incidence of sedation and weight gain. However, it may still cause side effects such as insomnia, dry mouth, and increased blood pressure in some patients. As with any medication, its use should be closely monitored by healthcare professionals to ensure efficacy and safety.

Formula: C₁₉H₂₃NO₃

InChI: InChI=1/C19H23NO3/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18/h3-11,18-20H,2,12-14H2,1H3/t18-,19-/s2

InChI key: InChIKey=CBQGYUDMJHNJBX-PVIFGLDDNA-N

SMILES: [C@@H](OC1=C(OCC)C=CC=C1)(C2=CC=CC=C2)[C@]3(CNCCO3)[H]

Synonyms:

• (2R)-2-[(R)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine
• (2R)-2-[(R)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine methanesulfonate (1:1)
• (2S)-2-[(S)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine
• (S,S)-2-[(2-ethoxyphenoxy)-phenylmethyl] morpholine
• 2-[(2-Ethoxyphenoxy)(Phenyl)Methyl]Morpholine
• Axs 12
• Morpholine, 2-[(R)-(2-ethoxyphenoxy)phenylmethyl]-, (2R)-rel-
• Norebox
• Prolift
• Reboxitine
• Vestra
• rel-(2R)-2-[(R)-(2-Ethoxyphenoxy)phenylmethyl]morpholine

Reboxetine

CAS: 71620-89-8

Formula: C₁₉H₂₃NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 313.3908

Ref: IN-DA005RFV

Reboxetine

CAS: 71620-89-8

Reboxetine

Purity: 98%

Molecular weight: 313.39g/mol

Ref: 54-OR1023348

Reboxetine

CAS: 71620-89-8

Reboxetine (Norebox) is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD.

Formula: C₁₉H₂₃NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 313.39

Ref: TM-T2579

Reboxetinemesylate

Controlled Product

CAS: 71620-89-8

Reboxetinemesylate is a prodrug that is converted to reboxetine, the active form of the drug. It has been shown to be effective in the treatment of symptoms related to depression and Parkinson's disease. Reboxetinemesylate has a long-term efficacy due to its long half-life and slow release from plasma proteins. This drug may have drug interactions with other medications, such as hepatic impairment or drugs that are metabolized by CYP450 enzymes. Reboxetinemesylate also has locomotor activity effects on rats, which may be due to dopamine receptor agonist properties. Reboxetinemesylate is not active against bacterial infections, but is used for the treatment of Parkinson's disease and depression.

Formula: C₂₀H₂₇NO₆S

Purity: Min. 95%

Molecular weight: 409.5 g/mol

Ref: 3D-FR148959