CAS 71653-63-9

Riodipine

Description:

Riodipine is a chemical compound classified as a calcium channel blocker, primarily used in the treatment of hypertension and certain cardiovascular conditions. It functions by inhibiting the influx of calcium ions through L-type calcium channels in vascular smooth muscle and cardiac tissue, leading to vasodilation and reduced blood pressure. Riodipine is characterized by its ability to selectively target these channels, which contributes to its therapeutic efficacy and safety profile. The compound typically exhibits good oral bioavailability and is metabolized in the liver, with its pharmacokinetics influenced by factors such as age and liver function. In terms of chemical structure, Riodipine contains a dihydropyridine ring, which is a common feature among many calcium channel blockers, contributing to its biological activity. As with any medication, potential side effects may include dizziness, headache, and peripheral edema, necessitating careful monitoring during treatment. Overall, Riodipine represents an important option in the management of cardiovascular diseases, reflecting the broader class of calcium channel blockers in clinical use.

Formula: C₁₈H₁₉F₂NO₅

InChI: InChI=1S/C18H19F2NO5/c1-9-13(16(22)24-3)15(14(10(2)21-9)17(23)25-4)11-7-5-6-8-12(11)26-18(19)20/h5-8,15,18,21H,1-4H3

InChI key: InChIKey=AZVFIZVKGSPGPK-UHFFFAOYSA-N

SMILES: C(OC)(=O)C=1C(C(C(OC)=O)=C(C)NC1C)C2=C(OC(F)F)C=CC=C2

Synonyms:

• Riodipine
• 3,5-Pyridinedicarboxylic acid, 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-, dimethyl ester
• PP 1466
• 3,5-Pyridinedicarboxylic acid, 4-[2-(difluoromethoxy)phenyl]-1,4-dihydro-2,6-dimethyl-, 3,5-dimethyl ester
• Foridon

Riodipine

CAS: 71653-63-9

Riodipine, a calcium channel blocker, is used as cardiovascular drugs.

Formula: C₁₈H₁₉F₂NO₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 367.34

Ref: TM-T26089