CAS 71675-85-9: Amisulpride
Description:Amisulpride is an atypical antipsychotic medication primarily used in the treatment of schizophrenia and depressive disorders. It belongs to the class of drugs known as substituted benzamides and is characterized by its selective antagonism of dopamine D2 and D3 receptors, which contributes to its antipsychotic effects. Amisulpride exhibits a unique pharmacological profile, as it can act as an antagonist at high doses and as a presynaptic dopamine release enhancer at low doses. This dual action is thought to contribute to its efficacy in treating both positive and negative symptoms of schizophrenia. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Its chemical structure includes a sulfonamide group, which is significant for its biological activity. Amisulpride is generally well-tolerated, but like all medications, it may have side effects, including weight gain and extrapyramidal symptoms. Its safety and efficacy have been established through various clinical trials, making it a valuable option in psychiatric medicine.
Formula:C17H27N3O4S
InChI:InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)
InChI key:InChIKey=NTJOBXMMWNYJFB-UHFFFAOYSA-N
SMILES:O=C(NCC1N(CC)CCC1)C=2C=C(C(N)=CC2OC)S(=O)(=O)CC
- Synonyms:
- 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
- 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
- Aminosultopride
- Amipride
- Barhemsys
- Benzamide, 4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-
- Dan 2163
- Deniban
- Joykem
- Paxiprid
- See more synonyms
- Socian
- Solian
- Amisulpride
- (±)-Amisulpride
