CAS 71675-85-9

Amisulpride

Description:

Amisulpride is an atypical antipsychotic medication primarily used in the treatment of schizophrenia and depressive disorders. It belongs to the class of drugs known as substituted benzamides and is characterized by its selective antagonism of dopamine D2 and D3 receptors, which contributes to its antipsychotic effects. Amisulpride exhibits a unique pharmacological profile, as it can act as an antagonist at high doses and as a presynaptic dopamine release enhancer at low doses. This dual action is thought to contribute to its efficacy in treating both positive and negative symptoms of schizophrenia. The substance is typically administered orally and is well-absorbed in the gastrointestinal tract. Its chemical structure includes a sulfonamide group, which is significant for its biological activity. Amisulpride is generally well-tolerated, but like all medications, it may have side effects, including weight gain and extrapyramidal symptoms. Its safety and efficacy have been established through various clinical trials, making it a valuable option in psychiatric medicine.

Formula: C₁₇H₂₇N₃O₄S

InChI: InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)

InChI key: InChIKey=NTJOBXMMWNYJFB-UHFFFAOYSA-N

SMILES: C(NCC1N(CC)CCC1)(=O)C2=C(OC)C=C(N)C(S(CC)(=O)=O)=C2

Synonyms:

• 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
• 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
• Aminosultopride
• Amipride
• Barhemsys
• Benzamide, 4-amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxy-
• Dan 2163
• Deniban
• Joykem
• Paxiprid
• Socian
• Solian
• Amisulpride
• (±)-Amisulpride
• 4-amino-n-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzam
• Amisulpride for system suitability
• DAN-2163, Deniban, 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
• Sulamid
• OCIAN
• AMisulpride(DAN 2163)
• 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-benzamide
• 4-aMino-5-(ethanesulfonyl)-N-{[(2S)-1-ethylpyrrolidin-2-yl]Methyl}-2-MethoxybenzaMide

Amisulpride

CAS: 71675-85-9

Formula: C₁₇H₂₇N₃O₄S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 369.48

Ref: 3B-A2450

Amisulpride

CAS: 71675-85-9

Color and Shape: Neat

Ref: 61-FOR0793.00

Amisulpride, 1mg/ml in Methanol

CAS: 71675-85-9

Color and Shape: Colourless

Ref: LP-AMS-1791-1LM

Amisulpride

CAS: 71675-85-9

Amisulpride

Formula: C₁₇H₂₇N₃O₄S

Purity: 100.0%

Color and Shape: White

Molecular weight: 369.17223

Ref: 47-1090

AMISULPRIDE CRS

CAS: 71675-85-9

AMISULPRIDE CRS

Formula: C₁₇H₂₇N₃O₄S

Color and Shape: White. Crystalline Powder. Powder.

Molecular weight: 369.479

Ref: 41-A0590000

Amisulpride for system suitability

CAS: 71675-85-9

Amisulpride for system suitability

Color and Shape: White

Ref: 47-1143

AMISULPRIDE FOR SYSTEM SUITABILITY CRS

CAS: 71675-85-9

AMISULPRIDE FOR SYSTEM SUITABILITY CRS

Formula: C₁₇H₂₇N₃O₄S

Molecular weight: 369.479

Ref: 41-Y0001534

Amisulpride

CAS: 71675-85-9

Formula: C₁₇H₂₇N₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 369.4790

Ref: IN-DA0063K4

Amisulpride

CAS: 71675-85-9

Amisulpride (Solian/Deniban), a dopamine antagonist antipsychotic, treats psychosis and schizophrenia in Europe/Australia, not in the US.

Formula: C₁₇H₂₇N₃O₄S

Purity: 99.97% - 99.99%

Color and Shape: White Or Almost White Crystalline Powder

Molecular weight: 369.48

Ref: TM-T0811

Amisulpride

CAS: 71675-85-9

Formula: C₁₇H₂₇N₃O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 369.48

Ref: 4Z-A-831

Amisulpride

CAS: 71675-85-9

Amisulpride

Purity: ≥98%

Molecular weight: 369.48g/mol

Ref: 54-BUP15780

Amisulpride

CAS: 71675-85-9

Amisulpride

Purity: 98%

Molecular weight: 369.48g/mol

Ref: 54-OR1029873

Amisulpride

CAS: 71675-85-9

Formula: C₁₇H₂₇N₃O₄S

Purity: ≥ 98.0% (dried basis)

Color and Shape: White or almost white crystalline powder

Molecular weight: 369.48

Ref: 7W-GP0164

Amisulpride 100 µg/mL in Acetonitrile

CAS: 71675-85-9

Formula: C₁₇H₂₇N₃O₄S

Color and Shape: Single Solution

Molecular weight: 369.48

Ref: 04-A10229750AL-100

Amisulpride

Controlled Product

CAS: 71675-85-9

Formula: C₁₇H₂₇N₃O₄S

Color and Shape: Neat

Molecular weight: 369.48

Ref: 04-C10229750

Amisulpride

CAS: 71675-85-9

Formula: C₁₇H₂₇N₃O₄S

Color and Shape: White

Molecular weight: 369.48

Ref: 86-MM0793.00

Amisulpride

CAS: 71675-85-9

Color and Shape: Neat

Ref: LP-AMS-1791-10

Amisulpride

Controlled Product

CAS: 71675-85-9

Applications Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.
References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),

Formula: C₁₇H₂₇N₃O₄S

Color and Shape: White

Molecular weight: 369.48

Ref: TR-A633250

Amisulpride

Controlled Product

CAS: 71675-85-9

Dopamine D2/D3 receptor antagonist; anti-psychotic;

Formula: C₁₇H₂₇N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 369.48 g/mol

Ref: 3D-FA17868

Amisulpride - Bio-X ™

Controlled Product

CAS: 71675-85-9

Amisulpride is an antipsychotic drug that has been used to treat schizophrenia. It is a dopamine receptor antagonist. Additionally, this drug has been researched and used to treat acute mania, schizoaffective disorder, and bipolar depression. Amisulpride works by binding to dopamine receptors in the brain which then blocks the action of dopamine. Amisulpride has been shown to be effective in treatment trials for schizophrenia that are resistant to standard treatments such as clozapine, haloperidol, or risperidone. In addition, this drug has been shown to be effective in reducing serum prolactin levels and improving cognitive performance in patients with schizophrenia.

Formula: C₁₇H₂₇N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 369.48 g/mol

Ref: 3D-BA164158