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CAS 71731-58-3

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Tiquizium bromide

Description:
Tiquizium bromide is a chemical compound classified as a quaternary ammonium salt, primarily used in the field of pharmacology. It is known for its role as a neuromuscular blocking agent, which means it can induce muscle relaxation during surgical procedures by blocking the transmission of nerve impulses to the muscles. The compound is characterized by its ability to selectively bind to nicotinic acetylcholine receptors at the neuromuscular junction, leading to paralysis of skeletal muscles. Tiquizium bromide is typically administered intravenously and is often utilized in conjunction with anesthetics to facilitate intubation and surgical interventions. Its pharmacokinetics involve rapid onset and a relatively short duration of action, making it suitable for use in various surgical settings. Safety and efficacy profiles are essential considerations, and it is important to monitor patients for potential side effects, including respiratory depression and cardiovascular effects. As with all neuromuscular blockers, careful dosing and patient monitoring are critical to ensure optimal outcomes during surgical procedures.
Formula:C19H24BrNS2
InChI:InChI=1/C19H24NS2.BrH/c1-20-11-3-2-6-16(20)10-9-15(14-20)19(17-7-4-12-21-17)18-8-5-13-22-18;/h4-5,7-8,12-13,16H,2-3,6,9-11,14H2,1H3;1H/q+1;/p-1/t16-,20-;/m1./s1
InChI key:InChIKey=VKBNGRDAHSELMQ-HKRZSZKNNA-M
SMILES:C(=C1C[N@+]2(C)[C@@](CC1)(CCCC2)[H])(C3=CC=CS3)C4=CC=CS4.[Br-]
Synonyms:
  • (5R,9aR)-3-(Di-2-thienylmethylene)-5-methyloctahydro-2H-quinolizinium bromide
  • (5R,9aR)-3-(dithiophen-2-ylmethylidene)-5-methyloctahydro-2H-quinolizinium bromide
  • 2H-Quinolizinium, 3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide (1:1), (5R,9aR)-rel-
  • 2H-Quinolizinium, 3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide, (5R,9aR)-rel-
  • 2H-Quinolizinium, 3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide, trans-
  • 2H-quinolizinium, 3-(di-2-thienylmethylene)octahydro-5-methyl-, bromide, (5R,9aR)- (1:1)
  • 71731-58-3
  • Hs 902
  • Hsr 902
  • Thiaton
  • See more synonyms
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  • Tiquizium Bromide
    TRC
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    Tiquizium Bromide

    Controlled Product
    CAS:

    Applications Tiquizium Bromide is a antimuscarinic agent that was used on airway smooth muscle in vitro and in patients with chronic obstructive pulmonary disease.
    References Shioya, T., et al.: Euro. J. Clin. Pharmacol., 50, 375 (1996); Nishikawa,T., et al.: Xenobiotica., 15, 1053 (1985);

    Formula:C19H24NS2·Br
    Color and Shape:Neat
    Molecular weight:410.43

    Ref: TR-T445120

    25mg
    179.00€
    50mg
    222.00€
    100mg
    310.00€