CAS 717824-30-1

Vidofludimus

Description:

Vidofludimus, with the CAS number 717824-30-1, is a chemical compound that belongs to the class of immunomodulatory agents. It is primarily characterized by its role as a selective inhibitor of the enzyme dihydroorotate dehydrogenase (DHODH), which is involved in the de novo synthesis of pyrimidines. This mechanism of action makes Vidofludimus particularly relevant in the context of autoimmune diseases, as it modulates the immune response by affecting lymphocyte proliferation. The compound has shown promise in clinical studies for conditions such as multiple sclerosis and rheumatoid arthritis. Vidofludimus is typically administered orally and has a favorable pharmacokinetic profile, which includes good absorption and a manageable half-life. Its safety and efficacy profile is still under investigation, but it is generally well-tolerated in clinical settings. As with any pharmaceutical agent, potential side effects and contraindications should be carefully considered in therapeutic applications.

Formula: C₂₀H₁₈FNO₄

InChI: InChI=1S/C20H18FNO4/c1-26-14-5-2-4-12(10-14)13-8-9-18(17(21)11-13)22-19(23)15-6-3-7-16(15)20(24)25/h2,4-5,8-11H,3,6-7H2,1H3,(H,22,23)(H,24,25)

InChI key: InChIKey=XPRDUGXOWVXZLL-UHFFFAOYSA-N

SMILES: C(NC1=C(F)C=C(C=C1)C2=CC(OC)=CC=C2)(=O)C3=C(C(O)=O)CCC3

Synonyms:

• SC12267
• 1-Cyclopentene-1-carboxylic acid, 2-[[(3-fluoro-3′-methoxy[1,1′-biphenyl]-4-yl)amino]carbonyl]-
• Vidofludimus
• 2-((3-Fluoro-3′-methoxy-[1,1′-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylic acid
• 2-[[(3-Fluoro-3′-methoxy[1,1′-biphenyl]-4-yl)amino]carbonyl]-1-cyclopentene-1-carboxylic acid

Vidofludimus

CAS: 717824-30-1

Formula: C₂₀H₁₈FNO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 355.3596

Ref: IN-DA00FC18

Vidofludimus

CAS: 717824-30-1

Vidofludimus

Purity: ≥98%

Molecular weight: 355.36g/mol

Ref: 54-BUP09701

Vidofludimus

CAS: 717824-30-1

Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH).

Formula: C₂₀H₁₈FNO₄

Purity: 98.33% - 99.58%

Color and Shape: Solid

Molecular weight: 355.36

Ref: TM-T2601

Vidofludimus

CAS: 717824-30-1

Vidofludimus is a cytotoxic drug that has been shown to have potent antiproliferative activity. It binds to the mitochondrial membrane potential, inhibiting the production of ATP and inducing apoptosis in cells. Vidofludimus has also been shown to be effective against autoimmune diseases, such as primary sclerosing cholangitis (PSC) and inflammatory bowel disease (IBD). Vidofludimus inhibits the production of cytokines by inhibiting nuclear factor kappa-B (NF-κB), which is an important mediator in the immune response. Vidofludimus has been shown to inhibit the synthesis of nucleotides, which may contribute to its efficacy in treating kidney fibrosis. Vidofludimus is a chemical inhibitor that blocks protein synthesis through inhibition of polysomes in cells.

Formula: C₂₀H₁₈FNO₄

Purity: Min. 95%

Molecular weight: 355.36 g/mol

Ref: 3D-FV102840