CAS 71800-37-8

(Des-Arg10,Leu9)-Kallidin

Description:

(Des-Arg10,Leu9)-Kallidin, also known by its CAS number 71800-37-8, is a synthetic peptide that is a derivative of the naturally occurring peptide kallidin, which is involved in various physiological processes, including vasodilation and inflammation. This compound is characterized by the absence of the arginine residue at position 10 and the substitution of leucine at position 9, which alters its biological activity compared to its parent compound. It typically exhibits properties such as being water-soluble and having a relatively low molecular weight, which facilitates its interaction with biological receptors. The peptide is primarily studied for its role in the kinin system, influencing blood pressure regulation and pain perception. Its specific structure allows it to bind to kinin receptors, potentially leading to various pharmacological effects. Research on (Des-Arg10,Leu9)-Kallidin contributes to the understanding of peptide signaling pathways and may have implications in therapeutic applications related to cardiovascular and inflammatory diseases.

Lys-(Des-Arg⁹,Leu⁸)-Bradykinin

CAS: 71800-37-8

B₁ bradykinin receptor antagonist.

Formula: C₄₇H₇₅N₁₃O₁₁

Purity: > 97%

Color and Shape: White Powder

Molecular weight: 998.19

Ref: 01-4030394

Lys-(des-Arg9, Leu8)-Bradykinin trifluoroacetate salt

CAS: 71800-37-8

Formula: C₄₇H₇₅N₁₃O₁₁

Molecular weight: 998.18

Ref: 7W-GM2577

Lys-(Des-Arg9,Leu8)-Bradykinin

CAS: 71800-37-8

Lys-(Des-Arg9,Leu8)-Bradykinin is a selective antagonist of the bradykinin B1 receptor [1].

Formula: C₄₇H₇₅N₁₃O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 998.18

Ref: TM-T80117

Lys-(Des-Arg9,Leu8)-Bradykinin trifluoroacetate salt

CAS: 71800-37-8

Bradykinin is a peptide that is released in response to injury and inflammation. It has two receptors, B1 and B2. Bradykinin binds to the B2 receptor which leads to vasodilation, increased vascular permeability, and bronchoconstriction. Lys-(Des-Arg9,Leu8)-Bradykinin trifluoroacetate salt H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Leu (LBP) is a synthetic analogue of bradykinin that competes with bradykinin for binding sites on the bradykinin b2 receptor. LBP also inhibits lipoxygenase activity in vitro and in animals. This drug can be used as an antagonist against bradykinin b2 receptor or as an antiplatelet agent.

Formula: C₄₇H₇₅N₁₃O₁₁

Purity: Min. 95%

Molecular weight: 998.18 g/mol

Ref: 3D-FL108717