CAS 7183-69-9

6α-Oxycodol

Description:

6α-Oxycodol, with the CAS number 7183-69-9, is a semi-synthetic opioid derived from codeine. It is characterized by its structural modifications that enhance its analgesic properties while potentially reducing some side effects associated with other opioids. This compound typically exhibits a high affinity for the mu-opioid receptors in the central nervous system, leading to its effectiveness in pain management. Its pharmacological profile includes analgesic, antitussive, and sedative effects, making it useful in clinical settings for treating moderate to severe pain. However, like other opioids, 6α-Oxycodol carries a risk of dependence, tolerance, and potential for abuse. The substance is often subject to regulatory controls due to its potential for misuse. In terms of physical properties, it is generally a white to off-white crystalline powder, soluble in organic solvents but less so in water. Safety and handling precautions are essential when working with this compound, as with all opioids, to mitigate risks associated with its use.

Formula: C₁₈H₂₃NO₄

InChI: InChI=1S/C18H23NO4/c1-19-8-7-17-14-10-3-4-12(22-2)15(14)23-16(17)11(20)5-6-18(17,21)13(19)9-10/h3-4,11,13,16,20-21H,5-9H2,1-2H3/t11-,13+,16-,17-,18+/m0/s1

InChI key: InChIKey=LHTAJTFGGUDLRH-QMVVXIJUSA-N

SMILES: O[C@]12[C@@]34C=5C(O[C@]3([C@@H](O)CC1)[H])=C(OC)C=CC5C[C@]2(N(C)CC4)[H]

Synonyms:

• 6α-Oxycodol
• Codeine B, dihydro-14-hydroxy-
• (5α,6α)-4,5-Epoxy-3-methoxy-17-methylmorphinan-6,14-diol
• Codeine, 7,8-dihydro-14-hydroxy-
• Morphinan-6,14-diol, 4,5-epoxy-3-methoxy-17-methyl-, (5α,6α)-

6α-Oxycodol (1mg/ml in Acetonitrile)

Controlled Product

CAS: 7183-69-9

Formula: C₁₈H₂₃NO₄

Color and Shape: Colourless

Molecular weight: 317.40

Ref: TR-KIT6810

6a-Oxycodol

Controlled Product

CAS: 7183-69-9

Applications 6α-Oxycodol is a dihydro metabolite of the analgesic opiate Oxycodone (O870600).
References Ishida, T. et al.: Drug Metab. Dispos., 7, 162 (1979); Moore, K.A. et al.: J. Anal. Toxicol., 27, 346 (2003); Lalovic, B. et al.: Clin. Pharmacol. Ther., 79, 461 (2006);

Formula: C₁₈H₂₃NO₄

Color and Shape: Neat

Molecular weight: 317.4

Ref: TR-O870580

6-α-Oxycodol-d3 (1.0mg/ml in Acetonitrile)

Controlled Product

CAS: 7183-69-9

Formula: C₁₈H₂₀D₃NO₄

Color and Shape: Single Solution

Molecular weight: 320.4

Ref: TR-KIT6815

6Alpha-Oxycodol-d3

Controlled Product

CAS: 7183-69-9

Applications Labelled analogue of 6α-Oxycodol, a dihydro metabolite of the analgesic opiate Oxycodone (O870600).
References Ishida, T. et al.: Drug Metab. Dispos., 7, 162 (1979); Moore, K.A. et al.: J. Anal. Toxicol., 27, 346 (2003); Lalovic, B. et al.: Clin. Pharmacol. Ther., 79, 461 (2006);

Formula: C₁₈H₂₀D₃NO₄

Color and Shape: Neat

Molecular weight: 320.4

Ref: TR-O870582

6α-Oxycodol

Controlled Product

CAS: 7183-69-9

6α-Oxycodol is an analytical method for the measurement of 6-keto-Δ5-pregnane steroids in urine samples. It is a reconstituted, reversed-phase high-performance liquid chromatography (RP-HPLC) method that uses a hydroxyl group as a chemical modifier. This validation study was conducted to compare the 6α-oxycodol assay with two other methods, LC-MS/MS and GC/MS, which are currently used to measure 6α-oxycodol in urine. The results of this study showed that the RP-HPLC method was the most accurate and precise.

Formula: C₁₈H₂₃NO₄

Purity: Min. 95%

Molecular weight: 317.4 g/mol

Ref: 3D-HAA18369