CAS 718630-59-2

PHA-793887

CAS: 718630-59-2

PHA-793887

Purity: ≥98%

Molecular weight: 361.48g/mol

Ref: 54-BUP06949

PHA-793887

CAS: 718630-59-2

Formula: C₁₉H₃₁N₅O₂

Molecular weight: 361.49

Ref: 4Z-P-356001

PHA-793887

CAS: 718630-59-2

PHA-793887 has been used in trials studying the treatment of Advanced/Metastatic Solid Tumors.

Formula: C₁₉H₃₁N₅O₂

Purity: 98.02% - >99.99%

Color and Shape: Solid

Molecular weight: 361.48

Ref: TM-T2113

PHA 793887

CAS: 718630-59-2

Inhibitor of cyclin dependend kinases

Formula: C₁₉H₃₁N₅O₂

Purity: Min. 95%

Color and Shape: Solid

Molecular weight: 361.24778

Ref: 3D-FM145343

PHA-793887

Controlled Product

CAS: 718630-59-2

Stability Hygroscopic
Applications PHA-793887 is a potent CDK (cyclin-dependent kinase) inhibitor. Recent studies shows that PHA-793887 has promising therapeutic activity against acute leukemias in vitro and in vivo. PHA-793887 was used to successfully modulate E2F transcriptional factor-dependent cell cycle, DNA replication, mitosis and apoptosis related gene in both tumors and skin biopsy from patients with solid tumors.
References Alzani, R. et al.: Exp. Hematol., 38, 259 (2010); Locatelli, G. et al.: Mol. Cancer Ther., 9, 1265 (2010); Brasca, M. et al.: Bioorg. Med. Chem., 18, 1844 (2010);

Formula: C₁₉H₃₁N₅O₂

Color and Shape: Neat

Molecular weight: 361.48

Ref: TR-P294480