CAS 71963-77-4: Artemether

Description:Artemether is an antimalarial compound derived from artemisinin, which is extracted from the sweet wormwood plant, Artemisia annua. It is primarily used in the treatment of malaria, particularly for cases caused by Plasmodium falciparum, including drug-resistant strains. Artemether is characterized by its rapid action against the malaria parasite, making it effective in reducing the severity of symptoms. The compound is typically administered in combination with lumefantrine to enhance efficacy and reduce the risk of resistance. Chemically, artemether is a sesquiterpene lactone with a complex structure that includes an endoperoxide bridge, which is crucial for its antimalarial activity. It is generally well-tolerated, but potential side effects may include nausea, vomiting, and dizziness. Artemether is usually available in oral formulations, but it can also be administered via intramuscular injection in severe cases. Its use is a key component of combination therapy strategies recommended by the World Health Organization to combat malaria effectively.

Formula:C₁₆H₂₆O₅

InChI:InChI=1S/C16H26O5/c1-9-5-6-12-10(2)13(17-4)18-14-16(12)11(9)7-8-15(3,19-14)20-21-16/h9-14H,5-8H2,1-4H3/t9-,10-,11+,12+,13+,14-,15-,16-/m1/s1

InChI key:InChIKey=SXYIRMFQILZOAM-HVNFFKDJSA-N

SMILES:O1OC23C4OC(OC)C(C)C3CCC(C)C2CCC1(O4)C

Synonyms:
(1R,4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0~4,13~.0~8,13~]hexadecane
(3R,5aS,6R,8aS,9R,10R,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-10-methoxy-3,6,9-trimethyldecahydro-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin
(4S,5R,8S,9R,10S,12R,13R)-10-Methoxy-1,5,9-trimethyl-11,14,15,16-tetraoxatetracyclo[10.3.1.0~4,13~.0~8,13~]hexadecane
3,12-Epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, [3R-(3α,5aβ,6β,8aβ,9α,10α,12β,12aR*)]-
3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (3R,5aS,6R,8aS,9R,10S,12R,12aR)-
3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin, decahydro-10-methoxy-3,6,9-trimethyl-, (5aS,6R,8aS,9R,10S,12R,12aR)-
Artemetero
Artemether [INN]
See more synonyms
Artemetherum
Artemos
Artenam
Artesaph
Artesian
Dihydroartemisinin methyl ether
Falcidol
Gvither
Larither
Malartem
Paluther
Sm 224
β-Artemether
β-Dihydroartemisinin methyl ether
Artemether

Found 15 products.

Product data	Purity	Price range	Estimated delivery
Artemether REF: 3B-A2190CAS: 71963-77-4	>98.0%(HPLC)	53.00 €~147.00 €	Fri 25 Apr 25
Artemether RS REF: 41-ICRS1408CAS: 71963-77-4	- - -	102.00 €	Wed 30 Apr 25
Artemether REF: 45-1042780CAS: 71963-77-4	- - -	429.00 €	Fri 02 May 25
Artemether REF: TM-T1323CAS: 71963-77-4	99.87% - 99.93%	54.00 €~78.00 €	Fri 02 May 25
Artemether REF: IN-DA00IKIWCAS: 71963-77-4	97%	33.00 €~243.00 €	Fri 02 May 25
Artemether REF: 54-BUP16738CAS: 71963-77-4	≥98%	94.00 €~116.00 €	Mon 05 May 25
Artemether REF: 54-OR1029058CAS: 71963-77-4	- - -	32.00 €~1,200.00 €	Mon 05 May 25
Artemether REF: 7W-GL9620CAS: 71963-77-4	≥ 98.0%	50.00 €	Mon 05 May 25
Artemether REF: 4Z-A-115003CAS: 71963-77-4	- - -	To inquire	Mon 05 May 25
Artemether REF: AC-46070CAS: 71963-77-4	- - -	To inquire	Mon 05 May 25
Artemether REF: 86-MM3252.00CAS: 71963-77-4	- - -	307.00 €	Mon 05 May 25
Artemether REF: BP-BP0195CAS: 71963-77-4	95%~99%	48.00 €~59.00 €	Mon 05 May 25
Artemether- 13C, d3 REF: TR-A777403CAS: 71963-77-4	- - -	423.00 €~2,867.00 €	Mon 12 May 25
Artemether REF: 3D-FA17991CAS: 71963-77-4	Min. 95%	108.00 €~1,275.00 €	Tue 13 May 25
Artemether REF: TR-A777400CAS: 71963-77-4	- - -	- - -	Discontinued product