CAS 71968-02-0

Aspochalasin D

Description:

Aspochalasin D is a natural product classified as a secondary metabolite, specifically belonging to the class of alkaloids. It is derived from certain fungal species, particularly those in the genus Aspergillus. This compound is characterized by its complex molecular structure, which includes multiple functional groups that contribute to its biological activity. Aspochalasin D has been studied for its potential pharmacological properties, including antimicrobial and cytotoxic effects, making it of interest in medicinal chemistry and drug development. Its mechanism of action often involves interference with cellular processes, which can lead to apoptosis in targeted cells. The compound's solubility and stability can vary depending on environmental conditions, influencing its bioavailability and efficacy. Additionally, Aspochalasin D's unique structural features may allow for further modifications to enhance its therapeutic potential. As research continues, the full scope of its applications and mechanisms remains an area of active investigation in the fields of natural products and pharmacology.

Formula: C₂₄H₃₅NO₄

InChI: InChI=1/C24H35NO4/c1-13(2)10-18-22-16(5)15(4)12-17-11-14(3)6-7-19(26)20(27)8-9-21(28)24(17,22)23(29)25-18/h8-9,11-13,16-20,22,26-27H,6-7,10H2,1-5H3,(H,25,29)/b9-8+,14-11-/t16-,17+,18+,19-,20+,22+,24-/m1/s1

InChI key: InChIKey=GCIKKGSNXSCKCP-WBEGXGIOSA-N

SMILES: O=C1[C@]23[C@]([C@H](CC(C)C)N1)([C@H](C)C(C)=C[C@@]2(/C=C(\C)/CC[C@@H](O)[C@@H](O)\C=C\C3=O)[H])[H]

Synonyms:

• Aspochalasin D
• 1H-Cycloundec[d]isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahydro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS,7E,11R,12S,13E,15aS)-
• (3S,3aR,4S,6aS,7E,11R,12S,13E,15aS)-3,3a,4,6a,9,10,11,12-Octahydro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-1H-cycloundec[d]isoindole-1,15(2H)-dione
• 10-Nor[11]cytochalasa-6,13,19-triene-1,21-dione, 17,18-dihydroxy-14-methyl-3-(2-methylpropyl)-, (3S,13E,17R,18S,19E)-
• (-)-Aspochalasin D
• isoaspochalasinC
• [3S,13E,17S,18S,19E,(-)]-17,18-Dihydroxy-14-methyl-3-(2-methylpropyl)-10-nor[11]cytochalasa-6,13,19-triene-1,21-dione
• 1H-Cycloundec(d)isoindole-1,15(2H)-dione, 3,3a,4,6a,9,10,11,12-octahyd ro-11,12-dihydroxy-4,5,8-trimethyl-3-(2-methylpropyl)-, (3S,3aR,4S,6aS ,7E,11R,12S,13E,15aS)-

Aspochalasin D

CAS: 71968-02-0

Formula: C₂₄H₃₅NO₄

Purity: 70.16%

Color and Shape: Yellow. Solid

Molecular weight: 402.0

Ref: 8R-CL0019

Aspochalasin D

CAS: 71968-02-0

Aspochalasin D

Molecular weight: 0.00g/mol

Ref: 54-BIBR1011

Aspochalasin D

CAS: 71968-02-0

Aspochalasin D, isolated from A. microcysticus, shows antibacterial properties and cytotoxicity affecting Ba/F3-V12 cells, with IC50s of 0.49 and 1.9 μg/ml.

Formula: C₂₄H₃₅NO₄

Color and Shape: Solid

Molecular weight: 401.54

Ref: TM-T37443

Aspochalasin D

CAS: 71968-02-0

Aspochalasin D is a mycotoxin belonging to the cytochalasin family, which is a secondary metabolite produced by fungi, specifically species such as Aspergillus. It acts by targeting actin filament dynamics, inhibiting actin polymerization, and consequently, affecting the integrity and function of the cytoskeleton. This inhibition of actin polymerization can disrupt cellular processes such as cell division, motility, and intracellular transport.

Formula: C₂₄H₃₅NO₄

Purity: Min. 95%

Molecular weight: 401.5 g/mol

Ref: 3D-WCA96802