CAS 71989-14-5

Fmoc-L-Asp(OtBu)-OH

Description:

Fmoc-L-Asp(OtBu)-OH, also known as Fmoc-protected L-aspartic acid with a tert-butyl ester group, is a chemical compound commonly used in peptide synthesis and organic chemistry. It features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely utilized for the protection of amino groups during peptide synthesis, allowing for selective deprotection under mild conditions. The presence of the tert-butyl (OtBu) ester group on the carboxylic acid of aspartic acid enhances the compound's stability and solubility, making it suitable for various synthetic applications. This compound is typically a white to off-white solid and is soluble in organic solvents such as dichloromethane and dimethylformamide. Its structure includes a chiral center, which contributes to its importance in the synthesis of biologically active peptides. The compound is sensitive to moisture and should be stored in a cool, dry place to maintain its integrity. Overall, Fmoc-L-Asp(OtBu)-OH is a valuable intermediate in the field of peptide chemistry.

Formula: C₂₃H₂₅NO₆

InChI: InChI=1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1

InChI key: InChIKey=FODJWPHPWBKDON-IBGZPJMESA-N

SMILES: C(OC(N[C@@H](CC(OC(C)(C)C)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-[(2-methylpropan-2-yl)oxy]-4-oxobutanoic acid
• (2S)-4-(tert-Butoxy)-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)-4-oxobutanoic acid
• (2S)-4-tert-Butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-butanoic acid
• (2S)-4-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-4-oxobutanoic acid (non-preferred name)
• (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-tert-butoxy-4-oxo-butanoic acid
• 4-tert-Butyl N-(fluoren-9-ylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-aspartate
• <span class="text-smallcaps">L</span>-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester
• FMOC-Asp(OtBu)-OH
• Fmoc-<span class="text-smallcaps">L</span>-Asp(OtBu)
• Fmoc-Asp(tBu)-OH
• Fmoc-DL-Asp(OtBu)-OH
• Fmoc-L-Asp(OtBu)-OH
• Fmoc-L-Asp(Tbu)-Oh
• Fmoc-L-Aspartic Acid Beta-Tert-Butyl Ester
• Fmoc-L-aspartic acid 4-tert-butyl ester
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-aspartic acid β-tert-butyl ester
• N-(9-Fluorenylmethoxycarbonyl)aspartic acid 4-tert-butyl ester
• L-Aspartic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 4-(1,1-dimethylethyl) ester

4-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-aspartate

CAS: 71989-14-5

Formula: C₂₃H₂₅NO₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 411.45

Ref: 3B-B3150

N-Fmoc-L-aspartic acid 4-tert-butyl ester, 98%

CAS: 71989-14-5

L-Aspartic acid is a nonessential amino acid that is used to biosynthesize other amino acids within the human body. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The orig

Formula: C₂₃H₂₄NO₆

Purity: 98%

Color and Shape: White to pale cream, Powder

Molecular weight: 410.45

Ref: 02-H59007

Fmoc-Asp(OtBu)-OH

CAS: 71989-14-5

M03404 - Fmoc-Asp(OtBu)-OH

Formula: C₂₃H₂₅NO₆

Purity: 98%

Color and Shape: Crystalline Powder,Powder

Molecular weight: 411.454

Ref: 10-M03404

Fmoc-L-Asp(OtBu)-OH

CAS: 71989-14-5

Formula: C₂₃H₂₅NO₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 411.4477

Ref: IN-DA0034XR

Fmoc-Asp(OtBu)-OH

CAS: 71989-14-5

Fmoc-Asp(OtBu)-OH

Purity: 98%

Color and Shape: Powder

Molecular weight: 411.45g/mol

Ref: 54-OR350180

Fmoc-Asp(OtBu)-OH

CAS: 71989-14-5

Formula: C₂₃H₂₅NO₆

Purity: ≥ 99.0%

Color and Shape: White powder

Molecular weight: 411.45

Ref: 7W-GM6999

Fmoc-Asp(OtBu)-OH

CAS: 71989-14-5

Fmoc-Asp(OtBu)-OH is a fluorescent probe that binds to the integrin receptor. This protein is a cell-surface receptor that binds to collagen, fibronectin and other extracellular matrix proteins. Fmoc-Asp(OtBu)-OH has been shown to inhibit the binding of human cells to collagen in a homogenous assay. The chemical ligation of this amino acid with an amine results in an isopeptide bond, which can be cleaved by trifluoroacetic acid. Fmoc-Asp(OtBu)-OH can be used for the detection of integrin receptors in mammalian cells and sectioned tissues.

Formula: C₂₃H₂₅NO₆

Purity: Min. 98.0 Area-%

Color and Shape: White Powder

Molecular weight: 411.45 g/mol

Ref: 3D-FF15779

Fmoc-Asp(OtBu)-OH

CAS: 71989-14-5

Fmoc-Asp(OtBu)-OH is a chemical compound that belongs to the group of modified amino acids. The synthesis of Fmoc-Asp(OtBu)-OH starts with the reaction of nicotinic acetylcholine, sodium carbonate, and chloride in trifluoroacetic acid. The product is then reacted with a disulfide bond and modified with polymerase chain and saponified. The final modification is achieved by reacting Fmoc-Asp(OtBu)-OH with messenger RNA (mRNA), which produces the desired product. Fmoc-Asp(OtBu)-OH has been shown to have minimal activity, as it does not elute from an ion exchange column under normal conditions. It also has no effect on acetylcholine release in rat hippocampal slices or on morphology when incubated in vitro for 24 hours at 37 degrees Celsius.

Formula: C₂₃H₂₅NO₆

Purity: Min. 98.0 Area-%

Molecular weight: 411.46 g/mol

Ref: 3D-FLD-1713-PI

Fmoc-Asp(OtBu)-OH

CAS: 71989-14-5

Formula: C₂₃H₂₅NO₆

Molecular weight: 411.5

Ref: ST-EA-CP-L28031

Fmoc-Asp(OtBu)-OH

CAS: 71989-14-5

Bachem ID: 4093142.

Formula: C₂₃H₂₅NO₆

Purity: 99.9%

Color and Shape: White

Molecular weight: 411.46

Ref: 01-4093142