CAS 71989-18-9
:N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
Description:
N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester, commonly referred to as Fmoc-L-Glu(γ-tBu)-OH, is a protected form of the amino acid L-glutamic acid. This compound is characterized by the presence of a 9-fluorenylmethoxycarbonyl (Fmoc) group, which serves as a protective group for the amino functionality, allowing for selective reactions during peptide synthesis. The γ-tert-butyl ester group provides additional protection for the carboxylic acid moiety, enhancing the stability and solubility of the compound in organic solvents. Fmoc-L-Glu(γ-tBu)-OH is typically used in solid-phase peptide synthesis, where it facilitates the stepwise assembly of peptides while preventing unwanted side reactions. The compound is generally stable under standard laboratory conditions but may require specific conditions for deprotection. Its structure contributes to its utility in biochemistry and medicinal chemistry, particularly in the synthesis of peptides with specific functional properties.
Formula:C24H27NO6
InChI:InChI=1S/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)/t20-/m0/s1
InChI key:InChIKey=OTKXCALUHMPIGM-FQEVSTJZSA-N
SMILES:C(OC(N[C@@H](CCC(OC(C)(C)C)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2
Synonyms:- (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
- (2S)-5-(tert-Butoxy)-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)-5-oxopentanoic acid
- (2S)-5-tert-Butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-pentanoic acid
- (2S)-5-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
- (4S)-5-tert-butoxy-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
- 5-tert-butoxy-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
- <span class="text-smallcaps">L</span>-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
- FMOC-Glu(OtBu)-OH
- Fmoc-L-glutamic acid 5-tert-butyl ester
- N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-glutamic acid γ-tert-butyl ester
- N-(9-Fluorenylmethoxycarbonyl)glutamic acid γ-tert-butyl ester
- N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
- L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
- See more synonyms
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Found 11 products.
N-Fmoc-L-glutamic acid 5-tert-butyl ester, 98%
CAS:<p>This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci</p>Formula:C24H27NO6Purity:98%Molecular weight:425.48Ref: IN-DA0038GY
1g28.00€5g28.00€10g25.00€1kg603.00€25g49.00€50g60.00€100g105.00€250g196.00€500g268.00€Fmoc-Glu(OtBu)-OH
CAS:Formula:C24H27NO6Purity:≥ 99.0%Color and Shape:White powderMolecular weight:425.48Fmoc-L-glutamic acid 5-tert-butyl ester
CAS:<p>Fmoc-L-glutamic acid 5-tert-butyl ester</p>Purity:≥98%Molecular weight:425.47g/mol5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate
CAS:Formula:C24H27NO6Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:425.48Fmoc-Glu(OtBu)-OH
CAS:<p>M03409 - Fmoc-Glu(OtBu)-OH</p>Formula:C24H27NO6Purity:99%Color and Shape:Powder or Crystalline Powder or SolidMolecular weight:425.481Fmoc-L-glutamic acid 5-tert-butyl ester
CAS:<p>Fmoc-L-glutamic acid 5-tert-butyl ester (Fmoc-Glu(OtBu)-OH) is a glutamic acid derivative.</p>Formula:C24H27NO6Purity:99.68%Color and Shape:SolidMolecular weight:425.47Fmoc-Glu(OtBu)-OH
CAS:<p>Fmoc-Glu(OtBu)-OH</p>Formula:C24H27NO6Purity:98%Color and Shape: white powderMolecular weight:425.47g/molFmoc-Glu(OtBu)-OH
CAS:<p>Fmoc-Glu(OtBu)-OH is an amino acid that is used in the synthesis of peptides and proteins. It is a hydrophilic, non-polar amino acid with a hydroxyl group at its carboxy terminus. This substance has been shown to inhibit the growth of cancer cells in vitro and has been used for the development of monoclonal antibodies. Fmoc-Glu(OtBu)-OH has also been shown to have pharmacokinetic properties that are different from other amino acids such as L-lysine, which may be due to its hydrophilic interactions with plasma proteins. This compound is also toxic, as shown by studies on rats where it was found to cause liver damage at high doses. Fmoc-Glu(OtBu)-OH binds to receptors on cells known as polysialic acid receptors, which are involved in cell adhesion and migration. Fmoc-Glu</p>Formula:C24H27NO6Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:425.47 g/molFMOC-L-Glutamic Acid 5-Tert-Butyl Ester (FMOC-Glu(OtBu)-OH) extrapure, 99%
CAS:Formula:C24H27NO6Purity:min. 99%Color and Shape:White to off-white, Crystalline powderMolecular weight:425.47
![5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3B%2Fthumb%2FB3167.jpg&w=3840&q=75)
