CAS 71989-26-9

Fmoc-Lys(Boc)-OH

Description:

Fmoc-Lys(Boc)-OH, also known as Fmoc-Lysine(Boc)-OH, is a protected amino acid commonly used in peptide synthesis. It features a lysine residue with two protective groups: the Fmoc (9-fluorenylmethoxycarbonyl) group, which is used to protect the amino group, and the Boc (tert-butyloxycarbonyl) group, which protects the side chain amino group of lysine. This compound is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. The presence of these protective groups allows for selective deprotection during the synthesis of peptides, facilitating the construction of complex peptide sequences. Fmoc-Lys(Boc)-OH is widely utilized in solid-phase peptide synthesis (SPPS) due to its stability and ease of handling. Its molecular structure includes a primary amine, a carboxylic acid, and two bulky protective groups, which contribute to its unique reactivity and compatibility in various synthetic pathways.

Formula: C₂₆H₃₂N₂O₆

InChI: InChI=1S/C26H32N2O6/c1-26(2,3)34-24(31)27-15-9-8-14-22(23(29)30)28-25(32)33-16-21-19-12-6-4-10-17(19)18-11-5-7-13-20(18)21/h4-7,10-13,21-22H,8-9,14-16H2,1-3H3,(H,27,31)(H,28,32)(H,29,30)/t22-/m0/s1

InChI key: InChIKey=UMRUUWFGLGNQLI-QFIPXVFZSA-N

SMILES: C(OC(N[C@@H](CCCCNC(OC(C)(C)C)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoic acid
• (2S)-6-(tert-Butoxycarbonylamino)-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]hexanoic acid
• (S)-2-[[[(9H-Fluoren-9-yl)methoxy]carbonyl]amino]-6-(tert-butoxycarbonylamino)hexanoic acid
• (S)-6-[(tert-Butoxycarbonyl)amino]-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]hexanoic acid
• <span class="text-smallcaps">L</span>-Lysine, N⁶-[(1,1-dimethylethoxy)carbonyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-L-Lys(Boc)-OH
• N-Alpha-Fmoc-Nepsilon-Boc-L-Lysine
• N-α-(Fmoc)-N-ε-(t-boc)-<span class="text-smallcaps">L</span>-Lysine-OH
• N-α-Fluorenylmethoxycarbonyl-N-ε-tert-butoxycarbonyl-<span class="text-smallcaps">L</span>-lysine
• N⁶-[(1,1-Dimethylethoxy)carbonyl]-N²-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-lysine
• N^α-(9-Fluorenylmethoxycarbonyl)-N^ε-(tert-butoxycarbonyl)lysine
• NSC 334302
• Nalpha-(9-Fluorenylmethoxycarbonyl)-Nepsilon-(Tert-Butoxycarbonyl)-L-Lysine
• Fmoc-Lys(Boc)-OH
• L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Nα-(9-Fluorenylmethoxycarbonyl)-Nε-(tert-butoxycarbonyl)lysine
• N-α-(Fmoc)-N-ε-(t-boc)-L-Lysine-OH

Nε-(tert-Butoxycarbonyl)-Nα-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-lysine

CAS: 71989-26-9

Formula: C₂₆H₃₂N₂O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 468.55

Ref: 3B-B3072

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

Bachem ID: 4003151.

Formula: C₂₆H₃₂N₂O₆

Purity: 99.7%

Color and Shape: White

Molecular weight: 468.55

Ref: 01-4003151

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

Formula: C₂₆H₃₂N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 468.5421

Ref: IN-DA0035C4

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

Formula: C₂₆H₃₂N₂O₆

Purity: ≥ 99.0%

Color and Shape: White powder

Molecular weight: 468.54

Ref: 7W-GM7550

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

Fmoc-Lys(Boc)-OH

Purity: ≥98%

Molecular weight: 468.54g/mol

Ref: 54-BUP19810

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

Fmoc-Lys(Boc)-OH

Formula: C₂₆H₃₂N₂O₆

Purity: 97%

Color and Shape: white powder

Molecular weight: 468.54g/mol

Ref: 54-OR350184

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

M03419 - Fmoc-Lys(Boc)-OH

Formula: C₂₆H₃₂N₂O₆

Purity: 98%

Color and Shape: Solid, Powder or Crystalline Powder or Solid or Chunks

Molecular weight: 468.55

Ref: 10-M03419

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

Fmoc-Lys(Boc)-OH (N-α-(Fmoc)-N-ε-(t-boc)-L-Lysine-OH) is a lysine derivative that acts as a reactive linker.

Formula: C₂₆H₃₂N₂O₆

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 468.54

Ref: TM-T67566

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

Fmoc-Lys(Boc)-OH is a monoclonal antibody that reacts with lysine residues. It is synthesized by reacting a solid phase support with an aliphatic hydrocarbon. The reactive functional group on the hydrocarbon terminates in an amine and forms an amide linkage to the amino terminus of the peptide. The hydroxyl terminus of the peptide is then reacted with a trifluoroacetic acid (TFA) ester of lysine in the presence of base. This reaction produces a TFA salt of Fmoc-Lys(Boc)-OH, which can be purified by high salt precipitation or reversed to produce Fmoc-Lys(Boc)-OH by treatment with base. Fmoc-Lys(Boc)-OH has been used as a reagent for chemical conjugation to fluorophores and other molecules such as biotin, avidin, strept

Formula: C₂₆H₃₂N₂O₆

Purity: Min. 98.0 Area-%

Molecular weight: 468.54 g/mol

Ref: 3D-FLK-1726-PI

Fmoc-Lys(Boc)-OH

CAS: 71989-26-9

Fmoc-Lys(Boc)-OH is a synthetic amino acid that has been used to synthesize polypeptides. It is prepared by the reaction of naphthalene, trifluoroacetic acid and copper (II) acetate in an acidic environment. The synthesis of Fmoc-Lys(Boc)-OH involves the use of a high salt and coordination geometry for the copper complex. This amino acid can be used as a cancer drug, because it inhibits NS3 protease, which is an enzyme that promotes tumor growth. Fmoc-Lys(Boc)-OH also binds to carbohydrate receptors on cancer cells and inhibits uptake of these cells by macrophages.

Formula: C₂₆H₃₂N₂O₆

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 468.54 g/mol

Ref: 3D-FF15876

Na-FMOC-Ne-BOC-L-Lysine (FMOC-Lys(BOC)-OH) extrapure, 98%

CAS: 71989-26-9

Formula: C₂₆H₃₂N₂O₆

Purity: min. 98%

Color and Shape: White to off-white, Crystalline powder

Molecular weight: 468.54

Ref: SR-20340