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CAS 72-40-2

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5-Aminoimidazole-4-carboxamide hydrochloride

Description:
5-Aminoimidazole-4-carboxamide hydrochloride, also known as AICA ribonucleotide or AICAR, is a chemical compound with the molecular formula C5H7N5O2·HCl. It is a white to off-white crystalline powder that is soluble in water and exhibits hygroscopic properties. This compound is characterized by the presence of an imidazole ring, an amino group, and a carboxamide functional group, which contribute to its biological activity. AICA has garnered attention in the field of biochemistry and pharmacology due to its role as a precursor in the biosynthesis of purine nucleotides and its potential effects on cellular metabolism. It is known to activate AMP-activated protein kinase (AMPK), which plays a crucial role in energy homeostasis. As a research chemical, it is often utilized in studies related to metabolic disorders, exercise physiology, and potential therapeutic applications. Safety data indicates that it should be handled with care, as with any chemical substance, and appropriate safety measures should be observed in laboratory settings.
Formula:C4H6N4O·ClH
InChI:InChI=1S/C4H6N4O.ClH/c5-3-2(4(6)9)7-1-8-3;/h1H,5H2,(H2,6,9)(H,7,8);1H
InChI key:InChIKey=MXCUYSMIELHIQL-UHFFFAOYSA-N
SMILES:C(N)(=O)C1=C(N)N=CN1.Cl
Synonyms:
  • 1H-Imidazole-4-carboxamide, 5-amino-, hydrochloride (1:1)
  • 1H-Imidazole-4-carboxamide, 5-amino-, monohydrochloride
  • 1H-Imidazole-4-carboxamide,5-amino-, hydrochloride
  • 4(5)-Amino-5(4)-imidazolecarboxamide hydrochloride
  • 4-Amino-5-carbamoylimidazole hydrochloride
  • 4-Amino-5-carbamoylimidazole salt of hydrochloric acid
  • 4-Amino-5-imidazolecarboxamide HCL
  • 4-Amino-5-imidazolecarboxamide hydrochloride
  • 4-Aminoimidazole-5-carboxamide hydrochloride
  • 4-amino-1H-imidazole-5-carboxamide HCL
  • See more synonyms
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