CAS 72003-83-9

Adenosine 5′-(trihydrogen diphosphate), 2′-deoxy-, sodium salt (1:2)

Description:

Adenosine 5′-(trihydrogen diphosphate), 2′-deoxy-, sodium salt (1:2), commonly referred to as dATP, is a nucleotide that plays a crucial role in cellular metabolism and energy transfer. It is a derivative of adenosine triphosphate (ATP) and is essential for DNA synthesis and repair, serving as a substrate for DNA polymerases during replication. The compound features a ribose sugar, a nitrogenous base (adenine), and a triphosphate group, which is responsible for its high-energy properties. As a sodium salt, it is typically more soluble in aqueous solutions, facilitating its biological functions. dATP is involved in various biochemical pathways, including cellular signaling and energy transfer, and is critical in the synthesis of nucleic acids. Its structure allows it to participate in enzymatic reactions, making it a vital component in molecular biology and biochemistry. The CAS number 72003-83-9 uniquely identifies this compound, ensuring precise reference in scientific literature and databases.

Formula: C₁₀H₁₅N₅O₉P₂·2Na

InChI: InChI=1S/C10H15N5O9P2.2Na/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(23-7)2-22-26(20,21)24-25(17,18)19;;/h3-7,16H,1-2H2,(H,20,21)(H2,11,12,13)(H2,17,18,19);;/t5-,6+,7+;;/m0../s1

InChI key: InChIKey=PMCITFSCGIPAKY-OJSHLMAWSA-N

SMILES: NC1=C2C(N(C=N2)[C@@H]3O[C@H](COP(OP(=O)(O)O)(=O)O)[C@@H](O)C3)=NC=N1.[Na]

Synonyms:

• 2'-Deoxyadenosine-5'-diphosphate,disodium salt
• 9H-purin-6-amine, 9-[2-deoxy-5-O-[hydroxy(phosphonooxy)phosphinyl]pentofuranosyl]-, sodium salt
• Adenosine 5'-(trihydrogen diphosphate), 2'-deoxy-, disodium salt
• Adenosine 5′-(trihydrogen diphosphate), 2′-deoxy-, sodium salt (1:2)
• dADP.Na3

disodium hydrogen ({[(2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate

CAS: 72003-83-9

Formula: C₁₀H₁₃N₅Na₂O₉P₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 455.1654

Ref: IN-DA00IC7O

2''-Deoxyadenosine 5''-diphosphate sodium salt

CAS: 72003-83-9

Formula: C₁₀H₁₂N₅Na₃O₉P₂

Purity: (HPLC) ≥ 95.0%

Color and Shape: White powder

Molecular weight: 477.15

Ref: 7W-GV9650

dADP disodium

CAS: 72003-83-9

dADP disodium

Purity: ≥98%

Molecular weight: 455.17g/mol

Ref: 54-BUP05548

dADP disodium

CAS: 72003-83-9

dADP disodium (2'-Deoxyadenosine 5'-di-phos-phate disodium) is widely found in plants and animals and is involved in the body's energy cycle.

Formula: C₁₀H₁₃N₅Na₂O₉P₂

Purity: 99.38%

Color and Shape: Solid

Molecular weight: 455.17

Ref: TM-T85317

2'-Deoxyadenosine-5'-diphosphate sodium salt

CAS: 72003-83-9

2'-Deoxyadenosine-5'-diphosphate sodium salt is a nucleotide that is involved in the synthesis of DNA. It is a structural analog of adenosine-5'-diphosphate and can be used as an experimental tool to study metabolic disorders. 2'-Deoxyadenosine-5'-diphosphate sodium salt binds to p2y receptors and blocks their activation, which inhibits cellular energy metabolism. This compound is structurally similar to adenosine-5'-triphosphate, but has been shown to inhibit the expansion of cells when heated, unlike adenosine-5'-triphosphate. 2'-Deoxyadenosine-5'-diphosphate sodium salt also inhibits cell proliferation in cancer cells and may have potential as a therapeutic agent for bowel disease.

Formula: C₁₀H₁₂N₅O₉P₂·xNa

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 408.18 g/mol

Ref: 3D-ND13490