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CAS 72025-60-6

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leukotriene C4

Description:
Leukotriene C4 (LTC4) is a potent lipid mediator involved in inflammatory responses and is part of the leukotriene family, which are derived from arachidonic acid. It is characterized by its role in bronchoconstriction, increased vascular permeability, and the recruitment of immune cells, particularly in conditions such as asthma and allergic reactions. LTC4 is a cysteinyl leukotriene, meaning it contains a cysteine residue, which contributes to its biological activity. It is typically synthesized by various immune cells, including mast cells and eosinophils, through the action of lipoxygenase enzymes. The substance is known to bind to specific leukotriene receptors, leading to various physiological effects. In terms of its chemical structure, LTC4 is a tripeptide composed of glutathione, which is modified by the addition of a leukotriene moiety. Due to its significant role in mediating inflammatory processes, LTC4 is a target for therapeutic interventions aimed at managing allergic and inflammatory diseases.
Formula:C30H47N3O9S
InChI:InChI=1S/C30H47N3O9S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(34)15-14-17-27(36)37)43-21-23(29(40)32-20-28(38)39)33-26(35)19-18-22(31)30(41)42/h6-7,9-13,16,22-25,34H,2-5,8,14-15,17-21,31H2,1H3,(H,32,40)(H,33,35)(H,36,37)(H,38,39)(H,41,42)/b7-6-,10-9-,12-11+,16-13+/t22-,23-,24-,25+/m0/s1
InChI key:InChIKey=GWNVDXQDILPJIG-NXOLIXFESA-N
SMILES:[C@@H](CS[C@@H]([C@H](CCCC(O)=O)O)/C=C/C=C/C=C\C/C=C\CCCCC)(NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O
Synonyms:
  • 5S,6R-LTC<sub>4</sub>
  • 5S,6R-Ltc(sub 4)
  • <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-<smallcap>L</span>-cysteinylglycine
  • Glycine, <span class="text-smallcaps">L</smallcap>-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraen-1-yl]-<smallcap>L</span>-cysteinyl-
  • Glycine, <span class="text-smallcaps">L</smallcap>-γ-glutamyl-S-[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]-<smallcap>L</span>-cysteinyl-
  • Glycine, N-(S-(1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl)-N-L-gamma-glutamyl-L-cysteinyl)-, (R-(R*,S*-(E,E,Z,Z)))-
  • Glycine, N-[S-[1-(4-carboxy-1-hydroxybutyl)-2,4,6,9-pentadecatetraenyl]-N-<span class="text-smallcaps">L</smallcap>-γ-glutamyl-<smallcap>L</span>-cysteinyl]-, [R-[R*,S*-(E,E,Z,Z)]]-
  • L-gamma-glutamyl-S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]pentadeca-2,4,6,9-tetraen-1-yl}-L-cysteinylglycine
  • LTC (sub 4)
  • LTC<sub>4</sub>
  • See more synonyms
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Found 4 products.
  • Leukotriene C4
    Apollo Scientific
    + Info

    Leukotriene C4

    CAS:
    Leukotriene C4
    Purity:≥95%

    Ref: 54-BUP23045

    25µg
    633.00€
  • Leukotriene C4
    Glentham
    + Info

    Leukotriene C4

    CAS:
    Formula:C30H47N3O9S
    Purity:≥ 95%
    Color and Shape:Liquid
    Molecular weight:625.77

    Ref: 7W-GL7123

    ne
    To inquire
  • Leukotriene C4
    Targetmol
    + Info

    Leukotriene C4

    CAS:
    Leukotriene C4 (LTC4) is an arachidonate lipid mediator that regulates leukocyte recruitment and function at sites of inflammation.
    Formula:C30H47N3O9S
    Purity:95.75%
    Color and Shape:Solid
    Molecular weight:625.77

    Ref: TM-T25687

    25µg
    449.00€
  • LTC4 (Leukotriene C4)
    TRC
    + Info

    LTC4 (Leukotriene C4)

    Controlled Product
    CAS:
    Formula:C30H47N3O9S
    Color and Shape:Neat
    Molecular weight:625.774

    Ref: TR-L473513

    2500µg
    19,421.00€