CAS 72040-64-3

6-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexanoic acid

Description:

The chemical substance known as 6-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexanoic acid, with the CAS number 72040-64-3, is a complex organic compound characterized by its unique structural features. It contains a thieno[3,4-d]imidazole ring, which contributes to its biological activity and potential pharmacological properties. The presence of multiple functional groups, including an amino group and a carboxylic acid, suggests that it may exhibit both hydrophilic and lipophilic characteristics, influencing its solubility and interaction with biological systems. The stereochemistry indicated by the (3aS,4S,6aR) configuration suggests specific spatial arrangements that can affect the compound's reactivity and binding affinity to biological targets. This compound may be of interest in medicinal chemistry, particularly in the development of therapeutic agents, due to its potential interactions with biological macromolecules. Further studies would be necessary to elucidate its specific properties, mechanisms of action, and potential applications in various fields.

Formula: C₁₆H₂₇N₃O₄S

InChI: InChI=1S/C16H27N3O4S/c20-13(17-9-5-1-2-8-14(21)22)7-4-3-6-12-15-11(10-24-12)18-16(23)19-15/h11-12,15H,1-10H2,(H,17,20)(H,21,22)(H2,18,19,23)/t11-,12-,15-/m0/s1

InChI key: InChIKey=CMUGHZFPFWNUQT-HUBLWGQQSA-N

SMILES: C(CCCC(NCCCCCC(O)=O)=O)[C@H]1[C@@]2([C@](CS1)(NC(=O)N2)[H])[H]

Synonyms:

• (+)-Biotin-Epsilon-Aminocaproic Acid
• 1H-Thieno[3,4-d]imidazole, hexanoic acid deriv.
• 6-(Biotinylamino)caproic acid
• 6-Biotinamidocaproic acid
• 6-[(Biotinyl)amino]hexanoic acid
• 6-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]hexanoic acid
• Biotin X
• Hexanoic acid, 6-[5-(tetrahydro-2-oxothieno[3,4-d]imidazolin-4-yl)valeramido]-
• Hexanoic acid, 6-[[5-(hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl)-1-oxopentyl]amino]-, [3aS-(3aα,4β,6aα)]-
• Hexanoic acid, 6-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]amino]-
• N-Biotinyl-6-aminohexanoic acid

6-Biotinamidohexanoic Acid

CAS: 72040-64-3

Formula: C₁₆H₂₇N₃O₄S

Purity: >97.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 357.47

Ref: 3B-B2433

Biotinyl-εAhx-OH

CAS: 72040-64-3

Biotin linked to a spacer for N-terminal modification.

Formula: C₁₆H₂₇N₃O₄S

Purity: 98.1%

Color and Shape: White Lyophilisate

Molecular weight: 357.47

Ref: 01-4029390

6-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoic acid

CAS: 72040-64-3

Formula: C₁₆H₂₇N₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 357.4683

Ref: IN-DA005NUU

6-Biotinamidohexanoic Acid

CAS: 72040-64-3

6-Biotinamidohexanoic Acid

Purity: 95%

Molecular weight: 357.47g/mol

Ref: 54-OR1011985

N-Biotinyl-6-aminohexanoic acid

CAS: 72040-64-3

N-Biotinyl-6-aminohexanoic acid

Purity: ≥98%

Molecular weight: 357.47g/mol

Ref: 54-BUP06499

N-(+)-Biotinyl-6-aminohexanoic acid

CAS: 72040-64-3

Formula: C₁₆H₂₇N₃O₄S

Purity: ≥ 97.0%

Color and Shape: White powder

Molecular weight: 357.47

Ref: 7W-GL8860

N-Biotinyl-6-aminohexanoic acid

CAS: 72040-64-3

N-Biotinyl-6-aminohexanoic acid (N-(+)-Biotinyl-6-aminohexanoic acid) can be used to perform N-terminal biotinylation.

Formula: C₁₆H₂₇N₃O₄S

Purity: 98.61%

Color and Shape: Solid

Molecular weight: 357.47

Ref: TM-T19444

Biotin caproic acid

CAS: 72040-64-3

Podophyllotoxin is a natural product that has been used in the treatment of cancer. Biotin caproic acid is a synthetic analogue of podophyllotoxin and has been shown to have potent antimicrobial activity. Podophyllotoxin is an inhibitor of microtubule polymerization, which leads to cell death. It also induces apoptosis by interacting with dopamine receptors on the cell surface and inhibiting their binding to dopamine. This inhibits dopamine-induced proliferation of cells, leading to cell death. Biotin caproic acid has been shown to have anticancer properties against human cancer cells in vitro. The mechanism of action may be due to binding to the cytochrome P450 enzyme and inhibiting its activity, which affects the metabolism of various drugs and hormones such as dopamine.

Formula: C₁₆H₂₇N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 357.47 g/mol

Ref: 3D-FB12176

6-(5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanoic acid

CAS: 72040-64-3

Formula: C₁₆H₂₇N₃O₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 357.47

Ref: 10-F241367

Biotin X

Controlled Product

CAS: 72040-64-3

Stability Hygroscopic! Store Under Inert Atmosphere.
Applications An active Biotinylation reagent.
References Giubellino, A., et al.: J. Med. Chem., 51, 7459 (2008), Wang, Z., et al.: Nat. Chem. Biol., 4, 557 (2008),

Formula: C₁₆H₂₇N₃O₄S

Color and Shape: Neat

Molecular weight: 357.47

Ref: TR-B395670