CAS 7207-68-3

2'-deoxy-5-fluoro-3',5'-di-O-hexadecanoyluridine

Description:

2'-Deoxy-5-fluoro-3',5'-di-O-hexadecanoyluridine, with the CAS number 7207-68-3, is a modified nucleoside that features a uridine base with specific chemical modifications. This compound is characterized by the presence of a deoxyribose sugar, which lacks an oxygen atom at the 2' position, and a fluorine atom at the 5' position of the uracil base, enhancing its stability and potentially altering its biological activity. The di-O-hexadecanoyl groups indicate that the molecule has two hexadecanoyl (fatty acid) chains attached to the 3' and 5' hydroxyl groups of the sugar, which can influence its solubility, membrane permeability, and interaction with biological systems. Such modifications are often employed to improve the pharmacokinetic properties of nucleoside analogs, making them more effective in therapeutic applications, particularly in antiviral and anticancer treatments. Overall, this compound exemplifies the structural diversity of nucleosides and their potential utility in medicinal chemistry.

Formula: C₄₁H₇₁FN₂O₇

InChI: InChI=1/C41H71FN2O7/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-38(45)49-33-36-35(31-37(50-36)44-32-34(42)40(47)43-41(44)48)51-39(46)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h32,35-37H,3-31,33H2,1-2H3,(H,43,47,48)/t35-,36+,37-/m0/s1