CAS 720710-69-0

L-Argininamide,N2-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-(9CI)

Description:

L-Argininamide, N2-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-lysyl-L-prolyl-L-leucylglycyl-L-leucyl-3-[(2,4-dinitrophenyl)amino]-L-alanyl-L-alanyl-(9CI) is a complex organic compound characterized by its intricate structure, which includes multiple amino acid residues and a benzopyran moiety. This compound features a combination of both hydrophilic and hydrophobic regions, contributing to its potential biological activity. The presence of the dinitrophenyl group suggests that it may have applications in biochemical assays or as a labeling agent. The methoxy and acetyl groups enhance its solubility and stability, while the amino acid sequence may influence its interactions with biological targets, such as enzymes or receptors. The compound's CAS number, 720710-69-0, allows for precise identification in chemical databases. Overall, this substance may be of interest in medicinal chemistry and pharmacology due to its potential therapeutic properties and the role of its components in biological systems.

Formula: C₅₅H₈₀N₁₆O₁₆

Synonyms:

• Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-Nh2
• Mocac-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-Nh2

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH₂

CAS: 720710-69-0

The N-terminal elongation of the widely used MMP FRET substrate Mca-PLGL-Dpa-AR-NH₂ with a Lys yields a fluorogenic peptide with improved substrate properties. As compared to Mca-PLGL-Dpa-AR-NH₂, the specificity constant (kcat/Km) of the broad-spectrum MMP-substrate Mca-KPLGL-Dpa-AR-NH₂ for collagenases (MMP-1, MMP-8, MMP-13) and MMP-14 is increased two- to ninefold and threefold, respectively, while those for gelatinases and matrilysin remain equally high.

Formula: C₅₅H₈₀N₁₆O₁₆

Purity: 99.0%

Color and Shape: Yellow Lyophilisate

Molecular weight: 1221.34

Ref: 01-4028885

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2

CAS: 720710-69-0

Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a quenched, fluorescent MMP peptide substrate designed for the real-time quantification of MMP enzymatic

Formula: C₅₅H₈₀N₁₆O₁₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 1221.32

Ref: TM-T78436

MOCAc-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2

CAS: 720710-69-0

MOCAc-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is a peptide that has been shown to inhibit the activity of ADAM17. It blocks the cleavage of proMMP1, MMP2, and MMP9 and inhibits collagenase, stromelysin, and cathepsin activities. This peptide may be useful for the prevention and treatment of diseases associated with excessive proteolytic activity such as arthritis or cancer.

Formula: C₅₅H₈₀N₁₆O₁₆

Purity: Min. 95%

Molecular weight: 1,221.35 g/mol

Ref: 3D-SMO-3670-PI

Mca-Lys-Pro-Leu-Gly-Leu-Dap (Dnp)-Ala-Arg-NH2 trifluoroacetate salt

CAS: 720710-69-0

Please enquire for more information about Mca-Lys-Pro-Leu-Gly-Leu-Dap (Dnp)-Ala-Arg-NH2 trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₅₅H₈₀N₁₆O₁₆

Purity: Min. 95%

Molecular weight: 1,221.32 g/mol

Ref: 3D-FM110947