CAS 72093-21-1

mastoparan

Description:

Mastoparan is a peptide derived from the venom of wasps, particularly from the species Vespula lewisii. It is characterized by its ability to interact with cell membranes and modulate various cellular processes. Structurally, mastoparan is composed of a sequence of amino acids that contribute to its amphipathic nature, allowing it to insert into lipid bilayers and disrupt membrane integrity. This property makes it a valuable tool in biochemical research, particularly in studies involving membrane dynamics and signal transduction. Mastoparan is known to activate G-proteins, which play a crucial role in transmitting signals from outside the cell to the inside, influencing various physiological responses. Additionally, it exhibits antimicrobial properties and has been studied for its potential applications in drug development and as a model for understanding membrane interactions. However, due to its origin from venom, caution is advised in its handling and application. Overall, mastoparan serves as an important compound in both toxicology and pharmacology research.

Formula: C₇₀H₁₃₁N₁₉O₁₅

InChI: InChI=1/C70H131N19O15/c1-17-40(11)55(75)69(103)88-53(35-54(74)90)68(102)87-52(34-39(9)10)67(101)83-46(25-19-22-28-71)62(96)78-45(16)61(95)86-50(32-37(5)6)65(99)79-42(13)58(92)77-43(14)60(94)85-51(33-38(7)8)66(100)80-44(15)59(93)81-47(26-20-23-29-72)63(97)82-48(27-21-24-30-73)64(98)89-56(41(12)18-2)70(104)84-49(57(76)91)31-36(3)4/h36-53,55-56H,17-35,71-73,75H2,1-16H3,(H2,74,90)(H2,76,91)(H,77,92)(H,78,96)(H,79,99)(H,80,100)(H,81,93)(H,82,97)(H,83,101)(H,84,104)(H,85,94)(H,86,95)(H,87,102)(H,88,103)(H,89,98)

SMILES: CCC(C)C(C(=NC(CC(=N)O)C(=NC(CC(C)C)C(=NC(CCCCN)C(=NC(C)C(=NC(CC(C)C)C(=NC(C)C(=NC(C)C(=NC(CC(C)C)C(=NC(C)C(=NC(CCCCN)C(=NC(CCCCN)C(=NC(C(C)CC)C(=NC(CC(C)C)C(=N)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N

Synonyms:

• Mastoparan Vespula Lewisii
• Mastoparan from Vespula lewisii
• H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2
• N-[1-[[5-amino-1-[[2-[[1-[[2-[[2-[[1-[[2-[[5-amino-1-[[5-amino-1-[[1-[(1-carbamoyl-3-methyl-butyl)carbamoyl]-2-methyl-butyl]carbamoyl]pentyl]carbamoyl]pentyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]amino]-1-methyl-2-oxo-ethyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]amino]-1-methyl-2-oxo-ethyl]carbamoyl]pentyl]carbamoyl]-3-methyl-butyl]-2-[(2-amino-3-methyl-pentanoyl)amino]butanediamide

Mastoparan

CAS: 72093-21-1

Bachem ID: 4013168.

Formula: C₇₀H₁₃₁N₁₉O₁₅

Purity: 96.9%

Color and Shape: White

Molecular weight: 1478.93

Ref: 01-4013168

Mastoparan (Vespula lewisii)

CAS: 72093-21-1

Formula: C₁₇H₂₉N₄O₄

Purity: 95%

Molecular weight: 353.4366

Ref: IN-DA006AFS

Mastoparan

CAS: 72093-21-1

Mastoparan is a peptide toxin from wasp venom. It has the chemical structure Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2.

Formula: C₇₀H₁₃₁N₁₉O₁₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 1478.91

Ref: TM-TP1386

Mastoparan

CAS: 72093-21-1

Formula: C₇₀H₁₃₁N₁₉O₁₅

Molecular weight: 1478.93

Ref: 7W-GL5641

Mastoparan Trifluoroacetic Acid Salt

Controlled Product

CAS: 72093-21-1

Applications Mastoparan Trifluoroacetic Acid Salt is a G-protein activator. Mastoparan activates phospholipase A2 and inhibits calmodulin.
References Delazari dos Santos, L., et al.: Proteomics, 12, 2682-2693 (2012);

Formula: C₇₀H₁₃₁N₁₉O₁₅·x(C₂HF₃O₂)

Color and Shape: Neat

Molecular weight: 1478.91 + x(114.02)

Ref: TR-M197603

Mastoparan

Controlled Product

CAS: 72093-21-1

A cell-penetrating peptide toxin whose sequence is derived from wasp venom and a potent activator of heterotrimeric G proteins. This product is available as a 0.5mg vial.
One letter code: INLKALAALAKKIL-NH2

Formula: C₇₀H₁₃₁N₁₉O₁₅

Purity: Min. 95%

Molecular weight: 1,478.9 g/mol

Ref: 3D-PMS-4107-V