CAS 7210-74-4

4-Methyl-2-(phenylmethyl)thiazole

Description:

4-Methyl-2-(phenylmethyl)thiazole is an organic compound characterized by its thiazole ring, which is a five-membered heterocyclic structure containing both sulfur and nitrogen atoms. This compound features a methyl group and a phenylmethyl group attached to the thiazole ring, contributing to its unique chemical properties. It typically appears as a colorless to pale yellow liquid or solid, depending on its purity and form. The presence of the thiazole moiety often imparts biological activity, making such compounds of interest in medicinal chemistry and pharmaceuticals. The compound may exhibit moderate to high lipophilicity due to the phenylmethyl group, influencing its solubility and interaction with biological membranes. Additionally, it may participate in various chemical reactions, such as electrophilic substitutions or nucleophilic attacks, due to the reactivity of the thiazole ring. Safety data should be consulted for handling and storage, as with any chemical substance, to ensure proper precautions are taken.

Formula: C₁₁H₁₁NS

InChI: InChI=1S/C11H11NS/c1-9-8-13-11(12-9)7-10-5-3-2-4-6-10/h2-6,8H,7H2,1H3

InChI key: InChIKey=YOSCSFCHAKAHDF-UHFFFAOYSA-N

SMILES: C(C=1SC=C(C)N1)C2=CC=CC=C2

Synonyms:

• 2-Benzyl-4-methylthiazole
• Thiazole, 2-benzyl-4-methyl-
• Thiazole, 4-methyl-2-(phenylmethyl)-
• 4-Methyl-2-(phenylmethyl)thiazole

2-Benzyl-4-methyl-1,3-thiazole

CAS: 7210-74-4

2-Benzyl-4-methyl-1,3-thiazole is a hydroxamic acid that has been shown to have antibacterial and antimicrobial properties. It is a selective inhibitor of the enzyme leishmanase, which is an enzyme that catalyzes the conversion of L-2,4-diaminobutanoate to L-2,4-diaminobutanoic acid. 2MBTT has been shown to have antiproliferative activity in cancer cells and also has antiviral activity against human immunodeficiency virus type 1 (HIV) and herpes simplex virus type 1 (HSV). This compound has shown antifungal activity against Candida albicans and Aspergillus fumigatus in vitro. Molecular modeling studies suggest that this compound binds to a site on the enzyme leishmanase that is not accessible by other inhibitors such as pyridoxal phosphate or EDTA. The maximal response

Formula: C₁₁H₁₁NS

Purity: Min. 95%

Molecular weight: 189.28 g/mol

Ref: 3D-HAA21074