CAS 72104-34-8

N2-Methyl Alfuzosin Hydrochloride

Description:

N2-Methyl Alfuzosin Hydrochloride is a chemical compound primarily used in the treatment of benign prostatic hyperplasia (BPH). It is a selective alpha-1 adrenergic antagonist, which works by relaxing the muscles in the prostate and bladder neck, thereby improving urine flow. The compound is characterized by its hydrochloride salt form, which enhances its solubility and stability in aqueous solutions. Structurally, it features a methyl group at the nitrogen position, which contributes to its pharmacological properties. The compound is typically administered orally and is known for its relatively favorable side effect profile compared to other medications in its class. Its mechanism of action involves blocking alpha-1 receptors, leading to vasodilation and reduced vascular resistance. As with many pharmaceuticals, the safety and efficacy of N2-Methyl Alfuzosin Hydrochloride are evaluated through clinical trials, and it is essential to consider potential interactions with other medications and contraindications in specific patient populations.

Formula: C₁₉H₂₈ClN₅O₄

Synonyms:

• Alfuzosin-EP-Imp-C
• Alfuzosin EP Impurity C HCl
• N-(3-(4-aMino-6,7-diMethoxyquinazolin-2-ylaMino)propyl)-N-Methyltetrahydrofuran-2-carboxaMide hydrochloride
• (RS)-N-[3-[(4-Amino-6,7-dimethoxyquinazolin-2-yl)amino]propyl]-N-methyltetrahydrofuran-2-carboxamide hydrochloride
• N2-Methyl Alfuzosin Hydrochloride
• Alfazosin EP Impurity C
• Alfuzosin Hydrochloride - Impurity C
• N-(3-(4-Amino-6,7-dimethoxyquinazolin-2-ylamino)propyl)-N-methyltetrahydrofuran-2-carboxamide
• Alfuzosin EP IMpurity C
• Alfuzosin Impurity 3（Alfuzosin EP Impurity C）
• (RS)-N-[3-[(4-AMino-6,7-diMethoxy-2-quinazolinyl)aMino]propyl]tetrahydro-N-Methyl-2-furancarboxaMide Hydrochloride

Alfuzosin EP Impurity C

CAS: 72104-34-8

Formula: C₁₉H₂₇N₅O₄HCl

Molecular weight: 389.5 : 36.5

Ref: ST-EA-CP-A71003

N2-Methyl alfuzosin Hydrochloride (1:x)

CAS: 72104-34-8

Formula: C₁₉H₂₇N₅O₄·ClH

Color and Shape: Neat

Ref: TR-M344640

N2-Methyl Alfuzosin

Controlled Product

CAS: 72104-34-8

Impurity Alfuzosin EP Impurity C
Applications N2-Methyl Alfuzosin (Alfuzosin EP Impurity C) is an impurity of Alfuzosin (A532000).
References Brogden, R.N., et al.: Drugs, 14, 163 (1977), Thien, T., et al.: Lancet, 1, 363 (1977),

Formula: C₁₉H₂₇N₅O₄·ClH

Color and Shape: Neat

Molecular weight: 425.91

Ref: TR-M276650

N2-Methyl alfuzosin hydrochloride (1:x)

CAS: 72104-34-8

Alfuzosin is a drug used to treat the signs and symptoms of benign prostatic hyperplasia (BPH). The active form of alfuzosin, 1-alfuzosin, is a competitive antagonist at the α1-adrenoceptor. Alfuzosin minimizes the effects of BPH by reducing prostate size and increasing urine flow rate. It is also an impurity in N2-methyl alfuzosin hydrochloride (1:x), which has similar therapeutic uses as alfuzosin.

Purity: Min. 95%

Ref: 3D-IM159048