CAS 72122-62-4

Beta-Casomorphin (Bovine)

Description:

Beta-Casomorphin (Bovine), with the CAS number 72122-62-4, is a peptide derived from the digestion of casein, a major protein found in cow's milk. It is classified as an opioid peptide due to its ability to bind to opioid receptors in the brain, which can influence pain perception, mood, and various physiological processes. This peptide consists of a sequence of amino acids that exhibit biological activity, including potential effects on gastrointestinal function and modulation of the immune system. Beta-Casomorphin is known for its role in the gut-brain axis, where it may affect neurobehavioral outcomes. Its presence in dairy products has raised interest in the fields of nutrition and health, particularly regarding its implications for individuals with lactose intolerance or those following specific dietary regimens. While research is ongoing, the safety and health effects of beta-casomorphin consumption remain subjects of scientific inquiry, with varying opinions on its potential benefits and drawbacks.

Formula: C₄₁H₅₅N₇O₉

InChI: InChI=1/C41H55N7O9/c1-3-25(2)35(41(56)57)45-38(53)32-13-7-19-46(32)34(50)24-43-36(51)31-12-8-21-48(31)40(55)30(23-26-10-5-4-6-11-26)44-37(52)33-14-9-20-47(33)39(54)29(42)22-27-15-17-28(49)18-16-27/h4-6,10-11,15-18,25,29-33,35,49H,3,7-9,12-14,19-24,42H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,56,57)/t25-,29-,30-,31-,32-,33-,35-/m0/s1

SMILES: CC[C@H](C)[C@@H](C(=O)O)N=C([C@@H]1CCCN1C(=O)CN=C([C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)N=C([C@@H]1CCCN1C(=O)[C@H](Cc1ccc(cc1)O)N)O)O)O

Synonyms:

• H-Tyr-Pro-Phe-Pro-Gly-Pro-Ile-OH
• L-tyrosyl-L-prolyl-L-phenylalanyl-L-prolylglycyl-L-prolyl-L-isoleucine
• BETA-CASOMORPHIN (1-7), BOVINE
• BETA-CASOMORPHIN-7 (BOVINE) 4H2O
• BETA-CASOMORPHIN-7 (BOVINE)
• L-TYR-PRO-PHE-PRO-GLY-PRO-ILE
• TYR-PRO-PHE-PRO-GLY-PRO-ILE 4H2O
• β-Casomorphin-7【ox】
• β-Casomorphin, bovine
• β-Casomorphin-7
• BETA CASOMORPHIN
• b-Casomorphin (1-7), bovine
• BETA-CASOMORPHIN-7
• TYR-PRO-PHE-PRO-GLY-PRO-ILE
• BETA-CASOMORPHIN (BOVINE)
• β-Casomorphin 7【ox】
• L-Isoleucine, L-tyrosyl-L-prolyl-L-phenylalanyl-L-prolylglycyl-L-prolyl-
• β-Casomorphin(cattle)
• β-Casomorphin (bovine)|BETA-CASOMORPHIN (BOVINE)
• b-Casomorphin (bovine)
• YPFPGPI
• Tyr-Pro-Phe-Pro-Gly-Pro-Ile-OH
• L-Tyr-L-Pro-L-Phe-L-Pro-Gly-L-Pro-L-Ile-OH
• β-Casomorphin, bovine(2TFA)

β-Casomorphin (bovine)

CAS: 72122-62-4

BCM-7, YPFPGPI, has first been isolated from an enzymatic casein digest. Only cow casein variants A1 and B yield this bioactive peptide after in vitro digestion with intestinal enzymes, but not the common A2 variant. β-Casomorphin displays opioid properties. The β-casomorphin generated by digestion of bovine milk could play a role in the aetiology of human diseases as type 1 diabetes and cardiovascular affections. In a rat model, BCM-7 attenuated the development of nephropathy in type I diabetes via inhibition of epithelial-mesenchymal transition of renal tubular epithelial cells.

Formula: C₄₁H₅₅N₇O₉

Purity: 98.7%

Color and Shape: White Powder

Molecular weight: 789.93

Ref: 01-4003340

ß-Casomorphin-7 (Bovine)

CAS: 72122-62-4

β-Casomorphin-7 (Bovine) is an opioid peptide that belongs to the class of casomorphins. It is a fragment of the larger ß-casomorphin molecule, which is derived from the breakdown of proline-rich proteins in cow milk. β-Casomorphin-7 has been shown to have potent bronchial and renal proximal effects in rats, as well as analgesic properties. It also inhibits aminopeptidase activity in lung explants and muscle tissues, which may be due to its ability to act on opioid receptors. β-Casomorphin-7 also has been shown to inhibit growth factor production and increase the production of factor β1 in a rat model of pulmonary fibrosis. This may be due to its ability to inhibit inflammation by acting on inflammatory cells such as macrophages or neutrophils.

Formula: C₄₁H₅₅N₇O₉•4H₂O

Purity: Min. 95%

Molecular weight: 861.98 g/mol

Ref: 3D-PEK-4078

Beta-Casomorphin-7 (Bovine)

CAS: 72122-62-4

Beta-Casomorphin-7 is a research tool that is used in the study of cell biology and pharmacology. It is an activator of the opioid receptor and a ligand for the receptor. The Beta-Casomorphin-7 (Bovine) antibody can be used to identify receptors on cells involved in protein interactions, ion channels, and high purity. It's CAS number is 72122-62-4.

Formula: C₄₁H₅₅N₇O₉

Purity: Min. 95%

Molecular weight: 789.92 g/mol

Ref: 3D-PEK-4078-V

β-Casomorphin (bovine)

CAS: 72122-62-4

Beta-casomorphin is a peptide that is derived from the digestion of the milk protein, casein. It has been found to bind to opioid receptors and has been shown to have both analgesic and antidiabetic effects in rats. Beta-casomorphin can be used as an analytical tool for determining the presence of bovine beta-casomorphin in various samples. The LC-MS/MS method is used for analysis, which detects oxidation products by mass spectrometry. This peptide has been studied in humans and mice. A polyclonal antibody against beta-casomorphin was generated in rabbits following immunization with a synthetic peptide fragment of this molecule. The antibody was then used to detect beta-casomorphin in human plasma.

Formula: C₄₁H₅₅N₇O₉

Purity: Min. 95%

Molecular weight: 789.92 g/mol

Ref: 3D-FC108651