CAS 72122-63-5

B-casomorphin fragment 1-5*hydrochloride bovine

Description:

B-casomorphin fragment 1-5 hydrochloride, with the CAS number 72122-63-5, is a peptide derived from the milk protein casein, specifically from the beta-casein variant found in bovine milk. This substance consists of a sequence of five amino acids and exhibits opioid-like activity, which means it can interact with opioid receptors in the body, potentially influencing pain perception and other physiological processes. As a hydrochloride salt, it is typically more soluble in water, enhancing its bioavailability for research and therapeutic applications. B-casomorphin has been studied for its potential effects on gastrointestinal function, neuroprotection, and its role in the modulation of mood and behavior. However, its use and effects can vary widely depending on dosage and individual biological factors. Safety and efficacy in humans require careful consideration, as with any bioactive peptide. Overall, B-casomorphin fragment 1-5 hydrochloride represents an interesting area of study within the fields of biochemistry and pharmacology.

Formula: C₃₀H₃₇N₅O₇

InChI: InChI=1/C30H37N5O7/c31-22(16-20-10-12-21(36)13-11-20)29(41)34-14-5-9-25(34)28(40)33-23(17-19-6-2-1-3-7-19)30(42)35-15-4-8-24(35)27(39)32-18-26(37)38/h1-3,6-7,10-13,22-25,36H,4-5,8-9,14-18,31H2,(H,32,39)(H,33,40)(H,37,38)/t22-,23-,24-,25?/m0/s1

Synonyms:

• .beta.-Casomorphin (1-5) (bovine)
• H-Tyr-Pro-Phe-Pro-Gly-OH
• L-tyrosylprolyl-L-phenylalanyl-L-prolylglycine
• β-Casomorphin-5【ox】
• β-Casomorphin-5
• β-Casomorphin (1-5), bovine
• BETA-CASOMORPHIN FRAGMENT 1-5
• 5-BROMO-4-CHLORO-3-INDOLYL-B-D-GALACTOPYRANOSIDE
• Glycine, L-tyrosyl-L-prolyl-L-phenylalanyl-L-prolyl-
• 5-BROMO-4-CHLORO-3-INDOLYL-B B-D-GALACTOPYRANOSIDE
• BETA-CASOMORPHIN BOVINE FRAGMENT 1-5 HYDROCHLORIDE
• Tyr-Pro-Phe-Pro-Gly-OH
• 5-BROMO-4-CHLORO-3-INDOYL-BETA-D-GALACTOSIDE
• 5-BROMO-4-CHLORO-3-INDOLYL-BETA -D-GALACTOSIDASE
• 5-BROMO-4-CHLORO-3-INDOLYL-BETA-D-GALACTOPYRANOSIDE
• 2-[[(2S)-1-[(2S)-2-[[1-[(2S)-2-azanyl-3-(4-hydroxyphenyl)propanoyl]pyrrolidin-2-yl]carbonylamino]-3-phenyl-propanoyl]pyrrolidin-2-yl]carbonylamino]ethanoic acid
• 5-BROMO-4-CHLORO-3-INDOLYL-BETA-D-GALATOPYRANOSIDE
• 5-BROMO-4-CHLORO-1H-INDOL-3-YL BETA-D-GALACTOPYRANOSIDE
• 5-BROMO-4-CHLORO-3-INDOYL-BETA-D-GALACTOPYRANOSIDE
• BETA-CASOMORPHIN-5 (BOVINE)
• 5-BROMO-4-CHLORO-3-INDOLYL-BETA-D-GALACTOPYRANOSIDE (X-GAL)
• 2-[[(2S)-1-[(2S)-2-[[1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenyl-propanoyl]pyrrolidine-2-carbonyl]amino]acetic acid
• X-BETA-D-GAL
• fragment1-5
• B-casomorphin fragment 1-5*hydrochloride bovine
• BETA-CASOMORPHIN-5
• TYR-PRO-PHE-PRO-GLY 2H2O
• READY TO USE X-GAL
• X-BETA-D-GALACTOSIDE
• b-Casomorphin (1-5), bovine
• BCIG
• 5-BROMO-4-CHLORO-3-INDOXYL-BETA-D-GALACTOPYRANOSIDE
• 5-BROMO-4-CHLORO-1H-INDOL-3-YL BETA-D-GALACTOSIDE-(1,5)
• 5-BROMO-4-CHLORO-3-INDLOLYL-B-D-GALACTOPYRANOSIDE
• X-GAL USP/EP/BP
• β-Casomorphin(1-5)
• X-GAL READY TO USE
• X-BETA-GAL
• BETA-CASOMORPHIN-5 (BOVINE) 2H2O
• β-Casomorphin 5【ox】
• 2-[[(2S)-1-[(2S)-2-[[1-[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]acetic acid
• β-casomorphin fragment 1-5 hydrochloride
• TYR-PRO-PHE-PRO-GLY HYDROCHLORIDE
• TYR-PRO-PHE-PRO-GLY
• Beta-Casomorphin (1-5) (bovine) acetate salt
• β-Casomorphin (1-5) (bovine)
• 5'-BROMO-4-CHLORO-3-INDOLYL-BETA-D-GALACTO-PYRANOSIDE

Beta-Casomorphin (1-5) (bovine) acetate salt

CAS: 72122-63-5

Beta-casomorphin (1-5) is a synthetic peptide that blocks opioid receptors. It has been shown to be an effective treatment for lung function in children with cystic fibrosis. Beta-casomorphin has also been shown to enhance the effectiveness of naloxone, an antagonist of opioid receptors, in blocking morphine-induced respiratory depression. This peptide was detected by LC-MS/MS methods and was found to be expressed in the hippocampal CA1 region of rats. Beta-casomorphin (1-5) can be analysed using a variety of spectrometry methods, including mass spectrometry and nuclear magnetic resonance spectroscopy.

Formula: C₃₀H₃₇N₅O₇

Purity: Min. 95%

Molecular weight: 579.65 g/mol

Ref: 3D-FC108654

ß-Casomorphin-5 (Bovine)

CAS: 72122-63-5

Beta-casomorphin-5 (BCM-5) is a peptide that is released from the digestion of casein in milk. It is an analog of casomorphin-7, which has been shown to have opioid activity. BCM-5 has been found to inhibit the proliferation of cells and induce apoptosis by binding to P21, a protein that controls the cell cycle. BCM-5 also binds to the mu-opioid receptor and inhibits gastric acid secretion. The conformational properties of BCM-5 have been determined with analytical methods such as LC/MS/MS, NMR, and FTIR. These studies have shown that BCM-5 adopts a ß-sheet conformation when bound to mucin glycoprotein or other proteins.

Formula: C₃₀H₃₇N₅O₇•2H₂O

Purity: Min. 95%

Molecular weight: 615.67 g/mol

Ref: 3D-PEK-4079

Beta-Casomorphin-5 (Bovine)

CAS: 72122-63-5

Beta-Casomorphin-5 is a peptide that is isolated from the milk of cows. It has been shown to activate the opioid receptor, and in doing so, inhibits ion channels and ligand-gated channels. Beta-Casomorphin-5 has also been shown to bind with high affinity to an antibody. Beta-Casomorphin-5 is used as a research tool for studying cell biology and pharmacology. It can be used as an inhibitor for certain ion channels and ligand-gated channels.

Formula: C₃₀H₃₇N₅O₇

Purity: Min. 95%

Molecular weight: 579.64 g/mol

Ref: 3D-PEK-4079-V