CAS 72131-33-0

Sulotroban

Description:

Sulotroban, with the CAS number 72131-33-0, is a chemical compound that functions primarily as a thromboxane A2 receptor antagonist. It is known for its potential therapeutic applications, particularly in the treatment of cardiovascular diseases, as it can inhibit platelet aggregation and vasoconstriction associated with thromboxane A2 activity. Sulotroban is characterized by its ability to selectively bind to thromboxane receptors, thereby modulating vascular tone and platelet function. The compound is typically administered in a pharmaceutical context, and its efficacy and safety profiles are evaluated through clinical studies. As with many pharmacological agents, its mechanism of action involves complex interactions at the molecular level, influencing various signaling pathways. Additionally, sulotroban's pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for understanding its therapeutic potential and optimizing its use in clinical settings. Overall, sulotroban represents a significant area of interest in cardiovascular pharmacotherapy.

Formula: C₁₆H₁₇NO₅S

InChI: InChI=1S/C16H17NO5S/c18-16(19)12-22-14-8-6-13(7-9-14)10-11-17-23(20,21)15-4-2-1-3-5-15/h1-9,17H,10-12H2,(H,18,19)

InChI key: InChIKey=XTNWJMVJVSGKLR-UHFFFAOYSA-N

SMILES: C(CNS(=O)(=O)C1=CC=CC=C1)C2=CC=C(OCC(O)=O)C=C2

Synonyms:

• Acetic acid, (4-(2-((phenylsulfonyl)amino)ethyl)phenoxy)-
• Sulotrobanum [Latin]
• (4-(2-((Phenylsulfonyl)amino)ethyl)phenoxy)acetic acid
• Sulotroban
• 2-[4-[2-[(Phenylsulfonyl)amino]ethyl]phenoxy]acetic acid
• BM 13177
• Acetic acid, [4-[2-[(phenylsulfonyl)amino]ethyl]phenoxy]-
• BM 13.177
• SKF 95587
• SK&F 95587
• (p-(2-Benzenesulfonamidoethyl)phenoxy)acetic acid
• Acetic acid, 2-[4-[2-[(phenylsulfonyl)amino]ethyl]phenoxy]-
• UNII-74574CO5A6
• BM 13177
• (4-{2-[(phenylsulfonyl)amino]ethyl}phenoxy)acetic acid
• Sulotrobanum

Sulotroban

CAS: 72131-33-0

sulotroban is a TXA2 receptor antagonist that acts synergistically with iloprost to inhibit TXA2-dependent platelet activation.

Formula: C₁₆H₁₇NO₅S

Purity: 98.86% - 99.98%

Color and Shape: Solid

Molecular weight: 335.37

Ref: TM-T68022

Sulotroban

CAS: 72131-33-0

Sulotroban

Purity: ≥98%

Molecular weight: 335.37g/mol

Ref: 54-BUP01047