D-(KLAKLAK)2, also known as a pro-apoptotic peptide, is a synthetic peptide that has garnered attention for its potential in cancer therapy due to its ability to induce apoptosis in malignant cells. This peptide consists of a repeating sequence of lysine (K) and leucine (L) amino acids, which contributes to its structural stability and biological activity. The pro-apoptotic properties of D-(KLAKLAK)2 are attributed to its ability to disrupt mitochondrial membranes, leading to the release of cytochrome c and subsequent activation of the apoptotic cascade. The peptide is typically characterized by its amphipathic nature, allowing it to interact effectively with lipid membranes. Additionally, it has been studied for its selective toxicity towards cancer cells while sparing normal cells, making it a promising candidate for targeted cancer therapies. Its CAS number, 721397-24-6, is a unique identifier that facilitates its identification in chemical databases and literature. Overall, D-(KLAKLAK)2 represents a significant advancement in the development of peptide-based therapeutics aimed at combating cancer.

d-(KLAKLAK)2, Proapoptotic Peptide

721397-24-6: D-(KLAKLAK)2, also known as a pro-apoptotic peptide, is a synthetic peptide that has garnered attention for its potential in cancer therapy due to its ability to induce apoptosis in malignant cells. This peptide consists of a repeating sequence of lysine (K) and leucine (L) amino acids, which contributes to its structural stability and biological activity. The pro-apoptotic properties of D-(KLAKLAK)2 are attributed to its ability to disrupt mitochondrial membranes, leading to the release of cytochrome c and subsequent activation of the apoptotic cascade. The peptide is typically characterized by its amphipathic nature, allowing it to interact effectively with lipid membranes. Additionally, it has been studied for its selective toxicity towards cancer cells while sparing normal cells, making it a promising candidate for targeted cancer therapies. Its CAS number, 721397-24-6, is a unique identifier that facilitates its identification in chemical databases and literature. Overall, D-(KLAKLAK)2 represents a significant advancement in the development of peptide-based therapeutics aimed at combating cancer.

<p>d-(KLAKLAK)2 is an antimicrobial and antitumor peptide, notable within the group of antimicrobial peptides, and exhibits strong anticancer properties. It kills bacteria by disrupting their cell membranes, causing leakage of cell contents. Additionally, d-(KLAKLAK)2 inhibits tumor cell proliferation by inducing apoptosis through mitochondrial swelling and membrane damage.</p>

CAS 721397-24-6

d-(KLAKLAK)2, Proapoptotic Peptide

d-(KLAKLAK)2, Proapoptotic Peptide

Ref: TM-TP2687