CAS 72165-34-5

(5alpha,6alpha)-3-ethoxy-7,8-didehydro-4,5-epoxymorphinan-6-ol

Description:

The chemical substance known as (5alpha,6alpha)-3-ethoxy-7,8-didehydro-4,5-epoxymorphinan-6-ol, with the CAS number 72165-34-5, is a synthetic derivative of morphinan, a class of compounds that includes various opiates and opioids. This compound features a complex polycyclic structure characteristic of morphinans, with specific stereochemistry at the 5 and 6 positions, which influences its biological activity. The presence of an ethoxy group at the 3 position and an epoxide at the 4,5 positions contributes to its unique pharmacological properties. Such modifications can affect the compound's solubility, receptor binding affinity, and overall potency. While specific biological activities may vary, compounds in this class are often studied for their potential analgesic effects and interactions with opioid receptors. As with many morphinan derivatives, understanding the structure-activity relationship is crucial for evaluating their therapeutic potential and safety profile.

Formula: C₁₈H₂₁NO₃

InChI: InChI=1/C18H21NO3/c1-2-21-14-6-3-10-9-12-11-4-5-13(20)17-18(11,7-8-19-12)15(10)16(14)22-17/h3-6,11-13,17,19-20H,2,7-9H2,1H3/t11-,12+,13-,17-,18-/m0/s1

Synonyms:

• Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-ethoxy-, (5alpha,6alpha)-

Norethylmorphine

Controlled Product

CAS: 72165-34-5

Applications Norethylmorphine is used in formation of ethylmorphine. Ethylmorphine is a metabolite in liver hepatocytes.
References Xu, B., et al.: Pharmacology & Toxicology, 73, 35 (1993),

Formula: C₁₈H₂₁NO₃

Color and Shape: Neat

Molecular weight: 299.36

Ref: TR-N721600